Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 2794041..2794651 Replicon chromosome
Accession NZ_CP104966
Organism Phyllobacterium sp. A18/5-2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N8E89_RS13920 Protein ID WP_106664813.1
Coordinates 2794041..2794349 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8E89_RS13925 Protein ID WP_245448832.1
Coordinates 2794397..2794651 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E89_RS13900 (N8E89_13895) 2789198..2790058 - 861 WP_106664807.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
N8E89_RS13905 (N8E89_13900) 2790221..2791063 + 843 WP_262260247.1 EamA family transporter -
N8E89_RS13910 (N8E89_13905) 2791065..2791712 - 648 WP_106664811.1 glutathione S-transferase family protein -
N8E89_RS13915 (N8E89_13910) 2791861..2793972 + 2112 WP_262260249.1 molybdopterin oxidoreductase family protein -
N8E89_RS13920 (N8E89_13915) 2794041..2794349 + 309 WP_106664813.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E89_RS13925 (N8E89_13920) 2794397..2794651 + 255 WP_245448832.1 putative addiction module antidote protein Antitoxin
N8E89_RS13930 (N8E89_13925) 2794670..2795233 - 564 WP_106664995.1 phosphoribosylglycinamide formyltransferase -
N8E89_RS13935 (N8E89_13930) 2795290..2796375 - 1086 WP_112760828.1 phosphoribosylformylglycinamidine cyclo-ligase -
N8E89_RS13940 (N8E89_13935) 2796559..2797100 + 542 Protein_2747 CDP-alcohol phosphatidyltransferase family protein -
N8E89_RS13945 (N8E89_13940) 2797168..2798280 + 1113 WP_162707280.1 AI-2E family transporter -
N8E89_RS13950 (N8E89_13945) 2798314..2798995 + 682 Protein_2749 DnaA regulatory inactivator HdaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-98)

Antitoxin

Uncharacterized protein HI1420

(2-73)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11634.41 Da        Isoelectric Point: 9.0575

>T259527 WP_106664813.1 NZ_CP104966:2794041-2794349 [Phyllobacterium sp. A18/5-2]
MNYSIEKTDTFLNWIEGLQDLRARARIMSRLDRLADGNFGDYKLLGEDVGEMRIDCGPGYRLYFTKQGGILIILLCGGDK
STQSRDIRKAKAMARDLKEIRS

Download         Length: 309 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 8891.26 Da        Isoelectric Point: 8.0082

>AT259527 WP_245448832.1 NZ_CP104966:2794397-2794651 [Phyllobacterium sp. A18/5-2]
MIEEYLLAVCEDGTSSEIARALGAIARARGITELAHKTGLTRQALYKALSGEGNPELATITKVAEALGLRLTLVRAPKNK
QDAA

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References