Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 2596137..2596704 Replicon chromosome
Accession NZ_CP104966
Organism Phyllobacterium sp. A18/5-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N8E89_RS12865 Protein ID WP_106667239.1
Coordinates 2596137..2596412 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8E89_RS12870 Protein ID WP_106667240.1
Coordinates 2596399..2596704 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E89_RS12855 (N8E89_12850) 2591762..2593191 + 1430 Protein_2531 HAMP domain-containing histidine kinase -
N8E89_RS12860 (N8E89_12855) 2593160..2596125 + 2966 Protein_2532 bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase -
N8E89_RS12865 (N8E89_12860) 2596137..2596412 - 276 WP_106667239.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E89_RS12870 (N8E89_12865) 2596399..2596704 - 306 WP_106667240.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N8E89_RS12875 (N8E89_12870) 2596772..2599105 - 2334 WP_106667241.1 PAS domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-87)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10407.16 Da        Isoelectric Point: 7.9936

>T259526 WP_106667239.1 NZ_CP104966:c2596412-2596137 [Phyllobacterium sp. A18/5-2]
VPVLEWRETARADLLAIMDYISDDSPAAAQQLKNEIEMKVLNLLKYPRSCKLGRVPGTREMIVRANYILIYTENVQAVSI
LRVLHAAQQWP

Download         Length: 276 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11535.07 Da        Isoelectric Point: 6.6435

>AT259526 WP_106667240.1 NZ_CP104966:c2596704-2596399 [Phyllobacterium sp. A18/5-2]
MATHTSMLHVRIDNKLKAQATETLGQFGLTVSDAVRILLTRIANDQALPVGLIADQETYDKWFRQKVQEALDDQRHPAIQ
HDDVMDEIQTMIDRKRHRAGS

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References