Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 1783539..1784004 Replicon chromosome
Accession NZ_CP104966
Organism Phyllobacterium sp. A18/5-2

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N8E89_RS08780 Protein ID WP_262261744.1
Coordinates 1783741..1784004 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag N8E89_RS08775 Protein ID WP_106662528.1
Coordinates 1783539..1783754 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E89_RS08765 (N8E89_08765) 1780299..1780751 + 453 WP_262261743.1 hypothetical protein -
N8E89_RS08770 (N8E89_08770) 1781028..1783470 + 2443 Protein_1725 DNA topoisomerase (ATP-hydrolyzing) subunit B -
N8E89_RS08775 (N8E89_08775) 1783539..1783754 - 216 WP_106662528.1 CopG family transcriptional regulator Antitoxin
N8E89_RS08780 (N8E89_08780) 1783741..1784004 - 264 WP_262261744.1 BrnT family toxin Toxin
N8E89_RS08785 (N8E89_08785) 1784290..1785345 + 1056 WP_262261745.1 dipeptidase -
N8E89_RS08790 (N8E89_08790) 1785391..1786998 + 1608 WP_262261869.1 ABC transporter substrate-binding protein -
N8E89_RS08795 (N8E89_08795) 1787026..1788093 + 1068 WP_106662531.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10208.80 Da        Isoelectric Point: 9.4462

>T259525 WP_262261744.1 NZ_CP104966:c1784004-1783741 [Phyllobacterium sp. A18/5-2]
MLFEYDPAKSASNKIKHGIDFEEAQPLWKEDRMLEAPAKVDGEPRFLVIGLLRGKHWSAICVYRSGKVRIISVRRARKQE
IEYYEDK

Download         Length: 264 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8402.52 Da        Isoelectric Point: 5.1351

>AT259525 WP_106662528.1 NZ_CP104966:c1783754-1783539 [Phyllobacterium sp. A18/5-2]
MKTSDFDRNFDEGEDIAEQVDWSKARRPNEELKRVNVDFPMWVVEGLDRQARRLGVTRQALIKLWIAERLG

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References