Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3515293..3515779 Replicon chromosome
Accession NZ_CP104965
Organism Devosia neptuniae strain A18/4-1

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag N8A98_RS20020 Protein ID WP_113120314.1
Coordinates 3515293..3515562 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag N8A98_RS20025 Protein ID WP_113120504.1
Coordinates 3515546..3515779 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8A98_RS20005 (N8A98_20005) 3511939..3512919 + 981 WP_262167973.1 arginase -
N8A98_RS20010 (N8A98_20010) 3512978..3514255 - 1278 WP_113120316.1 ATP-dependent Clp protease ATP-binding subunit ClpX -
N8A98_RS20015 (N8A98_20015) 3514430..3515056 - 627 WP_262167975.1 ATP-dependent Clp protease proteolytic subunit -
N8A98_RS20020 (N8A98_20020) 3515293..3515562 - 270 WP_113120314.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8A98_RS20025 (N8A98_20025) 3515546..3515779 - 234 WP_113120504.1 DUF6290 family protein Antitoxin
N8A98_RS20030 (N8A98_20030) 3515839..3516069 - 231 WP_262167977.1 hypothetical protein -
N8A98_RS20035 (N8A98_20035) 3516193..3516588 - 396 WP_262167978.1 YciI family protein -
N8A98_RS20040 (N8A98_20040) 3516722..3517978 + 1257 WP_262167980.1 cytochrome P450 -
N8A98_RS20045 (N8A98_20045) 3517996..3519162 - 1167 WP_262167981.1 class C beta-lactamase -
N8A98_RS20050 (N8A98_20050) 3519373..3520434 - 1062 WP_262167983.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10349.89 Da        Isoelectric Point: 10.5212

>T259524 WP_113120314.1 NZ_CP104965:c3515562-3515293 [Devosia neptuniae]
MAWTIEVDEHAARQFARLDRQDATRIRNYLRDRVATLDNPRQLGKALAGSKLGELWRYRVGDFRIICDLQDGRLVILVLG
VGHRSQVYR

Download         Length: 270 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8825.83 Da        Isoelectric Point: 4.6437

>AT259524 WP_113120504.1 NZ_CP104965:c3515779-3515546 [Devosia neptuniae]
MSKQTAVRLPDELYDRLQSLANRTGRTATFYIREAVEEHVQDLEDLYLAEDVLKRRAAGDNKTTSLDELSKRLGLDD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References