Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 1725526..1726217 Replicon chromosome
Accession NZ_CP104965
Organism Devosia neptuniae strain A18/4-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N8A98_RS11305 Protein ID WP_262171415.1
Coordinates 1725786..1726217 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N8A98_RS11300 Protein ID WP_262171413.1
Coordinates 1725526..1725789 (+) Length 88 a.a.

Genomic Context


N8A98_RS11280N8A98_RS11285N8A98_RS11290N8A98_RS11295N8A98_RS11300N8A98_RS11305
Location: 1722817..1723293 (477 bp)
Type: Others
Protein ID: WP_262171408.1
Location: 1723322..1724176 (855 bp)
Type: Others
Protein ID: WP_262171410.1
Location: 1724261..1724653 (393 bp)
Type: Others
Protein ID: WP_262171411.1
Location: 1724750..1725372 (623 bp)
Type: Others
Protein ID: Protein_1737
Location: 1725526..1725789 (264 bp)
Type: Antitoxin
Protein ID: WP_262171413.1
Location: 1725786..1726217 (432 bp)
Type: Toxin
Protein ID: WP_262171415.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
N8A98_RS11280 (N8A98_11280)1722817..1723293+477WP_262171408.1GNAT family protein-
N8A98_RS11285 (N8A98_11285)1723322..1724176+855WP_262171410.1aminoglycoside phosphotransferase family protein-
N8A98_RS11290 (N8A98_11290)1724261..1724653+393WP_262171411.1DUF4440 domain-containing protein-
N8A98_RS11295 (N8A98_11295)1724750..1725372+623Protein_1737glycerol-3-phosphate 1-O-acyltransferase PlsY-
N8A98_RS11300 (N8A98_11300)1725526..1725789+264WP_262171413.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
N8A98_RS11305 (N8A98_11305)1725786..1726217+432WP_262171415.1type II toxin-antitoxin system VapC family toxinToxin

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-128)

Antitoxin

(8-75)


Sequences


Toxin        


Download         Length: 144 a.a.        Molecular weight: 16059.49 Da        Isoelectric Point: 4.3576

>T259523 WP_262171415.1 NZ_CP104965:1725786-1726217 [Devosia neptuniae]
VSFLLDTNVLSEIRRPQPDQQVLTWLDQVDEDRTYLSVITIAEIARGVALMDDGRRRNELAQWLELDLPARFGDRILPVD
TQIALIWGKLLASTRKEGIGLSVMDGWIAATAIALQLVLVTRNTRDFENLPLTLLDPWSPPAA

Download         Length: 432 bp


Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9560.87 Da        Isoelectric Point: 5.8395

>AT259523 WP_262171413.1 NZ_CP104965:1725526-1725789 [Devosia neptuniae]
MSATKKQEAWTVANAKAHLSEVIERAQSEPQMITRNGTPSVVIVSVEEWNRKTERKGSLATFLLSSPLAGTELADARLLD
EPRDLAL

Download         Length: 264 bp


Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References