Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) brnT-shpB/BrnT_toxin-BrnA
Location 1192741..1193248 Replicon chromosome
Accession NZ_CP104965
Organism Devosia neptuniae strain A18/4-1

Toxin (Protein)


Gene name brnT Uniprot ID -
Locus tag N8A98_RS08530 Protein ID WP_262170644.1
Coordinates 1192973..1193248 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID -
Locus tag N8A98_RS08525 Protein ID WP_262170642.1
Coordinates 1192741..1192992 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8A98_RS08500 (N8A98_08500) 1188449..1189162 + 714 WP_262170639.1 molybdopterin-synthase adenylyltransferase MoeB -
N8A98_RS08505 (N8A98_08505) 1189355..1190581 - 1227 WP_262170640.1 beta-ketoacyl-ACP synthase I -
N8A98_RS08510 (N8A98_08510) 1190671..1191201 - 531 WP_113121920.1 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabA -
N8A98_RS08515 (N8A98_08515) 1191457..1191831 + 375 WP_262171925.1 Fur family transcriptional regulator -
N8A98_RS08520 (N8A98_08520) 1192057..1192734 + 678 WP_262171926.1 class I SAM-dependent methyltransferase -
N8A98_RS08525 (N8A98_08525) 1192741..1192992 - 252 WP_262170642.1 BrnA antitoxin family protein Antitoxin
N8A98_RS08530 (N8A98_08530) 1192973..1193248 - 276 WP_262170644.1 BrnT family toxin Toxin
N8A98_RS08535 (N8A98_08535) 1193420..1194256 + 837 WP_262170645.1 arylamine N-acetyltransferase -
N8A98_RS08540 (N8A98_08540) 1194257..1194853 + 597 WP_262170647.1 YdeI/OmpD-associated family protein -
N8A98_RS08545 (N8A98_08545) 1194850..1195371 + 522 WP_262170648.1 DUF1697 domain-containing protein -
N8A98_RS08550 (N8A98_08550) 1195391..1196284 + 894 WP_262170649.1 ribokinase -
N8A98_RS08555 (N8A98_08555) 1196378..1196914 - 537 WP_262171927.1 translation initiation factor IF-3 -
N8A98_RS08560 (N8A98_08560) 1197065..1197841 + 777 WP_262170650.1 alpha/beta hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-82)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(24-78)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10428.78 Da        Isoelectric Point: 7.3177

>T259522 WP_262170644.1 NZ_CP104965:c1193248-1192973 [Devosia neptuniae]
MPYEWDEAKNRANRLKHGISFEEAQLIFAGPVFSWVDTRLDYGETRIVSIGLISGIVAVTVVHTDRNGTTRIISARLANQ
RERTIYDDHLR

Download         Length: 276 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9550.83 Da        Isoelectric Point: 8.4039

>AT259522 WP_262170642.1 NZ_CP104965:c1192992-1192741 [Devosia neptuniae]
MTTISDKRLAELAKRRDEQIDYSDIPELDEQFWANAQLVEPDGTQQVTLRVKKSVLEAYKATGKGYQTRMNAVLESYAKT
LRK

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References