Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 340060..340824 Replicon plasmid p_unnamed1
Accession NZ_CP104964
Organism Devosia neptuniae strain A18/4-1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag N8A98_RS01620 Protein ID WP_262165250.1
Coordinates 340351..340824 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag N8A98_RS01615 Protein ID WP_113123739.1
Coordinates 340060..340347 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8A98_RS01595 (N8A98_01595) 335072..336094 + 1023 WP_262165243.1 hydroxyacid dehydrogenase -
N8A98_RS01600 (N8A98_01600) 336091..336870 + 780 WP_262165244.1 sugar phosphate isomerase/epimerase -
N8A98_RS01605 (N8A98_01605) 336885..338132 + 1248 WP_262165246.1 glucarate dehydratase family protein -
N8A98_RS01610 (N8A98_01610) 338153..338893 + 741 WP_262165247.1 ribonuclease activity regulator RraA -
N8A98_RS01615 (N8A98_01615) 340060..340347 + 288 WP_113123739.1 DUF1778 domain-containing protein Antitoxin
N8A98_RS01620 (N8A98_01620) 340351..340824 + 474 WP_262165250.1 GNAT family N-acetyltransferase Toxin
N8A98_RS01625 (N8A98_01625) 340910..341164 + 255 WP_162740478.1 hypothetical protein -
N8A98_RS01630 (N8A98_01630) 341229..341708 - 480 WP_262165253.1 hypothetical protein -
N8A98_RS01635 (N8A98_01635) 341902..342168 - 267 WP_262165254.1 hypothetical protein -
N8A98_RS01640 (N8A98_01640) 342203..342574 - 372 WP_262165256.1 hypothetical protein -
N8A98_RS01645 (N8A98_01645) 342764..345502 + 2739 WP_262165257.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..532786 532786


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(1-93)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17132.82 Da        Isoelectric Point: 9.7521

>T259520 WP_262165250.1 NZ_CP104964:340351-340824 [Devosia neptuniae]
MQAPSRLSEQHRLEDFSSGEVVLDTWLKTRALPNQAAGVSRTYVAVEGGQVAGYYCLSSAAISLKEAPRALRHGMPDPLP
MILMGRLAVDQRYKGQGLGTALLKDSVLRAQSALEIIGVRGLLVHALHDQAKGFYLHHGFRETPGNPLTLVLPFKFT

Download         Length: 474 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10534.14 Da        Isoelectric Point: 5.1351

>AT259520 WP_113123739.1 NZ_CP104964:340060-340347 [Devosia neptuniae]
MPAKEDQKISTSVPINLRIPREAQLMIDRAAKLSGKNRTEFMVEAAMAAAEDKLLDQAFIALDAQAYAQFLDVLDRGPEP
EGYKRLMSAPSPWGK

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References