259515

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yjhX-yjhQ/YjhX-GNAT
Location 4798818..4799637 Replicon chromosome
Accession NZ_CP104925
Organism Klebsiella pasteurii strain AHM8C130-1I

Toxin (Protein)


Gene name yjhX Uniprot ID -
Locus tag N5863_RS22635 Protein ID WP_004129235.1
Coordinates 4799380..4799637 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yjhQ Uniprot ID -
Locus tag N5863_RS22630 Protein ID WP_087828273.1
Coordinates 4798818..4799369 (-) Length 184 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5863_RS22605 (N5863_22600) 4794454..4795218 + 765 WP_049115075.1 SDR family NAD(P)-dependent oxidoreductase -
N5863_RS22610 (N5863_22605) 4795267..4795686 + 420 WP_004129251.1 RbsD/FucU family protein -
N5863_RS22615 (N5863_22610) 4795730..4796776 - 1047 WP_004129248.1 LacI family DNA-binding transcriptional regulator -
N5863_RS22620 (N5863_22615) 4797172..4797918 - 747 WP_117085590.1 class I SAM-dependent methyltransferase -
N5863_RS22625 (N5863_22620) 4798345..4798704 - 360 Protein_4449 class I SAM-dependent methyltransferase -
N5863_RS22630 (N5863_22625) 4798818..4799369 - 552 WP_087828273.1 N-acetyltransferase Antitoxin
N5863_RS22635 (N5863_22630) 4799380..4799637 - 258 WP_004129235.1 YjhX family toxin Toxin
N5863_RS22640 (N5863_22635) 4800221..4801405 + 1185 WP_049115080.1 mannonate dehydratase -
N5863_RS22645 (N5863_22640) 4801482..4802957 + 1476 WP_112165899.1 fructuronate reductase -
N5863_RS22650 (N5863_22645) 4803095..4803871 + 777 WP_004129229.1 Uxu operon transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Putative toxin of bacterial toxin-antitoxin pair

(1-85)

Antitoxin

GNAT domain

(25-121)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9568.07 Da        Isoelectric Point: 11.1381

>T259515 WP_004129235.1 NZ_CP104925:c4799637-4799380 [Klebsiella pasteurii]
MNLSRQEQRTLHVLAKGGRIAHVRDTSGRVTSVECYSREGLLLSDCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRA
QLDNR

Download         Length: 258 bp

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20098.02 Da        Isoelectric Point: 7.5099

>AT259515 WP_087828273.1 NZ_CP104925:c4799369-4798818 [Klebsiella pasteurii]
MTNHSFTFHVASEGDTDDILNVETRAFGYSKEARLVASLLNDESACPTLSLLARHNGKAVGHILFTRAMFKGEPDSPMMH
ILAPLAVVPEYQGAGVGGALIRHGIEQLKTMGSQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEAHKACWMLQRLSS
QPLGRTGQIQCARALMKPEHWRE

Download         Length: 552 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References