Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc-RelB
Location 4732386..4732981 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag RS71_RS21010 Protein ID WP_057084910.1
Coordinates 4732386..4732763 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag RS71_RS21015 Protein ID WP_057084912.1
Coordinates 4732760..4732981 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS20990 4727691..4728722 + 1032 WP_038922999.1 methionine synthase -
RS71_RS20995 4728888..4729778 - 891 WP_057084906.1 oxidoreductase -
RS71_RS21000 4729909..4730532 - 624 WP_057084908.1 glutathione S-transferase -
RS71_RS21005 4730818..4732209 + 1392 WP_057084955.1 ATP-binding protein -
RS71_RS21010 4732386..4732763 - 378 WP_057084910.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
RS71_RS21015 4732760..4732981 - 222 WP_057084912.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
RS71_RS21020 4733122..4734270 - 1149 WP_022633801.1 L-threonine dehydrogenase -
RS71_RS21025 4734657..4735112 + 456 WP_022633802.1 NUDIX domain-containing protein -
RS71_RS21030 4735184..4735861 - 678 WP_057084914.1 respiratory nitrate reductase subunit gamma -
RS71_RS21035 4735861..4736580 - 720 WP_022633804.1 nitrate reductase molybdenum cofactor assembly chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(5-120)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-52)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14341.45 Da        Isoelectric Point: 4.9149

>T259506 WP_057084910.1 NZ_CP104920:c4732763-4732386 [Dickeya solani]
MKWVSAQDVIDFHDRILQVLPDVVVMADPGRAEALVYRVQNRLYYEGVTELFELAATYWVTIARGHIFNDGNKHTAFFVT
MIFLRRNGILIVDNDNSLEELTIKAATGECLVSELAEQLRQRVEK

Download         Length: 378 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8149.29 Da        Isoelectric Point: 7.2019

>AT259506 WP_057084912.1 NZ_CP104920:c4732981-4732760 [Dickeya solani]
MKTYTITEARQNIAAVIDTAASGEPVEIKRRDGTSAVLIPKAEFEAYQKAKLDAEFDFIMQRHGHTIKALADR

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References