Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 3776721..3777352 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag RS71_RS16880 Protein ID WP_057082664.1
Coordinates 3777077..3777352 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag RS71_RS16875 Protein ID WP_057082663.1
Coordinates 3776721..3777080 (-) Length 120 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS16845 3771721..3772638 + 918 WP_057082660.1 iron-siderophore ABC transporter substrate-binding protein -
RS71_RS16850 3772635..3773657 + 1023 WP_050571369.1 iron ABC transporter permease -
RS71_RS16855 3773650..3774699 + 1050 WP_081020579.1 iron ABC transporter permease -
RS71_RS16860 3774711..3775556 + 846 WP_057082661.1 ABC transporter ATP-binding protein -
RS71_RS16865 3775553..3776218 + 666 WP_057082662.1 RraA family protein -
RS71_RS16870 3776221..3776631 - 411 WP_022633005.1 type II toxin-antitoxin system HicB family antitoxin -
RS71_RS16875 3776721..3777080 - 360 WP_057082663.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
RS71_RS16880 3777077..3777352 - 276 WP_057082664.1 type II toxin-antitoxin system HicA family toxin Toxin
RS71_RS16885 3777482..3778537 - 1056 WP_057082665.1 MBL fold metallo-hydrolase -
RS71_RS16890 3779056..3782103 + 3048 WP_072143081.1 formate dehydrogenase-N subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(30-88)

Antitoxin

Uncharacterised protein family HicB

(60-112)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10140.67 Da        Isoelectric Point: 10.7783

>T259501 WP_057082664.1 NZ_CP104920:c3777352-3777077 [Dickeya solani]
MKEQVRSLRKRQKSTLEQVFKSPVQSGIKWADIESLIKALGGDVKEGRGSRCKFLLNGSIANFHRPHPSPDTDKGAVANL
RDWLESIGVKP

Download         Length: 276 bp

Antitoxin


Download         Length: 120 a.a.        Molecular weight: 13307.04 Da        Isoelectric Point: 4.9313

>AT259501 WP_057082663.1 NZ_CP104920:c3777080-3776721 [Dickeya solani]
MSKPSAPNTIEIAGQPAVISYVPELGAFRGKFLGLTGYCDFVSDSIQGLKKEGEISLREYIDDCSTSGIEPYTRQEKIKT
FTLRYPESFGERLNQAAAEHEISVNSFIIETLNERMKHV

Download         Length: 360 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References