259500

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 3694661..3695441 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name dhiT Uniprot ID A0A2K8W4P2
Locus tag RS71_RS16495 Protein ID WP_022632927.1
Coordinates 3694661..3694918 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID A0A2K8W4X0
Locus tag RS71_RS16500 Protein ID WP_022632928.1
Coordinates 3694926..3695441 (+) Length 172 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS16485 3691427..3693577 - 2151 WP_057082614.1 formate dehydrogenase subunit alpha -
RS71_RS16490 3693612..3694154 - 543 WP_022632926.1 4Fe-4S dicluster domain-containing protein -
RS71_RS16495 3694661..3694918 + 258 WP_022632927.1 DUF4160 domain-containing protein Toxin
RS71_RS16500 3694926..3695441 + 516 WP_022632928.1 DUF2442 domain-containing protein Antitoxin
RS71_RS16505 3695520..3696017 - 498 WP_022632929.1 hydrogenase maturation peptidase HycI -
RS71_RS16510 3696010..3696408 - 399 WP_057082615.1 formate hydrogenlyase maturation HycH family protein -
RS71_RS16515 3696405..3697196 - 792 WP_022632931.1 NADH-quinone oxidoreductase subunit B family protein -
RS71_RS16520 3697193..3697762 - 570 WP_022632932.1 hydrogenase 4 subunit H -
RS71_RS16525 3697773..3699500 - 1728 WP_022632933.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-74)

Antitoxin

Uncharacterized protein HI1420

(80-157)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10007.56 Da        Isoelectric Point: 8.1243

>T259500 WP_022632927.1 NZ_CP104920:3694661-3694918 [Dickeya solani]
MPEVDRLAGLIFHLYFYDDERHYLPHVHVCYGNHELIISIRTGTEIEGYLPNNKRKMALAHIRAHREQLLSMWERAVVGR
NPGKL

Download         Length: 258 bp

Antitoxin


Download         Length: 172 a.a.        Molecular weight: 19099.82 Da        Isoelectric Point: 5.2747

>AT259500 WP_022632928.1 NZ_CP104920:3694926-3695441 [Dickeya solani]
MHKIVEVDVIGDFSLRLTYDDGLVCDINLYQYASSPVFSDVSLFIKFGLLPDGALEWLPDIKISASELRKKGEYVSHTLA
VRERHFADVISRAFYDAVIENRPEILQAALKIAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTHVSLATVVSLAHTVLQLE
ELQLEDLQLEE

Download         Length: 516 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8W4P2

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W4X0

References