Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3242097..3242722 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name Hha Uniprot ID A0A2K8W3K4
Locus tag RS71_RS14655 Protein ID WP_022632574.1
Coordinates 3242097..3242300 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID A0A2K8W3I1
Locus tag RS71_RS14660 Protein ID WP_022632575.1
Coordinates 3242354..3242722 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS14625 3237719..3238057 + 339 WP_002208627.1 P-II family nitrogen regulator -
RS71_RS14630 3238100..3239392 + 1293 WP_022632570.1 ammonium transporter AmtB -
RS71_RS14635 3239487..3240350 - 864 WP_057084532.1 acyl-CoA thioesterase II -
RS71_RS14640 3240622..3241179 + 558 WP_057084531.1 YbaY family lipoprotein -
RS71_RS14645 3241208..3241537 - 330 WP_057084530.1 MGMT family protein -
RS71_RS14655 3242097..3242300 - 204 WP_022632574.1 HHA domain-containing protein Toxin
RS71_RS14660 3242354..3242722 - 369 WP_022632575.1 Hha toxicity modulator TomB Antitoxin
RS71_RS14665 3243230..3243373 - 144 WP_022632576.1 type B 50S ribosomal protein L36 -
RS71_RS14670 3243389..3243640 - 252 WP_022632577.1 type B 50S ribosomal protein L31 -
RS71_RS14675 3243817..3246963 - 3147 WP_022632578.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8161.52 Da        Isoelectric Point: 8.8580

>T259499 WP_022632574.1 NZ_CP104920:c3242300-3242097 [Dickeya solani]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFYSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14223.06 Da        Isoelectric Point: 5.1663

>AT259499 WP_022632575.1 NZ_CP104920:c3242722-3242354 [Dickeya solani]
MDEYTPQHYDIAQLRFLCENLHDESIATLGDSSHGWVNDPTSAVNLQLNELIEHIAAFVVTYKIKYPHEAALCERVEKYL
DDTYILFSNYGINDTELRKWQKSKSQLFRMFSEKSICTVVKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K8W3K4

Antitoxin

Source ID Structure
AlphaFold DB A0A2K8W3I1

References