Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3032141..3032667 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag RS71_RS13685 Protein ID WP_057085415.1
Coordinates 3032141..3032446 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID E0SK21
Locus tag RS71_RS13690 Protein ID WP_012773205.1
Coordinates 3032449..3032667 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS13660 3027241..3027423 + 183 WP_155518235.1 hypothetical protein -
RS71_RS13665 3027570..3028712 + 1143 WP_057085423.1 Fic family protein -
RS71_RS13670 3029051..3029344 + 294 WP_057085421.1 DUF1778 domain-containing protein -
RS71_RS13675 3029341..3029835 + 495 WP_057085420.1 GNAT family N-acetyltransferase -
RS71_RS13680 3030119..3031861 + 1743 WP_072143211.1 TIGR04141 family sporadically distributed protein -
RS71_RS13685 3032141..3032446 - 306 WP_057085415.1 type II toxin-antitoxin system toxin CcdB Toxin
RS71_RS13690 3032449..3032667 - 219 WP_012773205.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
RS71_RS13695 3032726..3033469 - 744 WP_057085413.1 MobC family replication-relaxation protein -
RS71_RS13700 3033611..3033781 + 171 WP_155518234.1 hypothetical protein -
RS71_RS13705 3034380..3034721 - 342 WP_057085460.1 hypothetical protein -
RS71_RS13710 3034907..3035059 + 153 WP_155518233.1 YlcI/YnfO family protein -
RS71_RS13715 3035400..3036320 + 921 WP_057085410.1 5'-nucleotidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11694.56 Da        Isoelectric Point: 4.6533

>T259498 WP_057085415.1 NZ_CP104920:c3032446-3032141 [Dickeya solani]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPLIEAHNLSEKVNKTLFPLIRIDGEDYRLMTTELSSVPVEVIGEAI
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8201.16 Da        Isoelectric Point: 7.2038

>AT259498 WP_012773205.1 NZ_CP104920:c3032667-3032449 [Dickeya solani]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIKAEEWKKENREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB E0SK21

References