Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3029051..3029835 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag RS71_RS13675 Protein ID WP_057085420.1
Coordinates 3029341..3029835 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag RS71_RS13670 Protein ID WP_057085421.1
Coordinates 3029051..3029344 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS13645 3024553..3025566 + 1014 WP_057085431.1 zinc-binding dehydrogenase -
RS71_RS13650 3025794..3026135 + 342 WP_057085428.1 helix-turn-helix domain-containing protein -
RS71_RS13655 3026352..3026931 + 580 Protein_2650 transposase -
RS71_RS13660 3027241..3027423 + 183 WP_155518235.1 hypothetical protein -
RS71_RS13665 3027570..3028712 + 1143 WP_057085423.1 Fic family protein -
RS71_RS13670 3029051..3029344 + 294 WP_057085421.1 DUF1778 domain-containing protein Antitoxin
RS71_RS13675 3029341..3029835 + 495 WP_057085420.1 GNAT family N-acetyltransferase Toxin
RS71_RS13680 3030119..3031861 + 1743 WP_072143211.1 TIGR04141 family sporadically distributed protein -
RS71_RS13685 3032141..3032446 - 306 WP_057085415.1 type II toxin-antitoxin system toxin CcdB -
RS71_RS13690 3032449..3032667 - 219 WP_012773205.1 type II toxin-antitoxin system antitoxin CcdA -
RS71_RS13695 3032726..3033469 - 744 WP_057085413.1 MobC family replication-relaxation protein -
RS71_RS13700 3033611..3033781 + 171 WP_155518234.1 hypothetical protein -
RS71_RS13705 3034380..3034721 - 342 WP_057085460.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17684.53 Da        Isoelectric Point: 7.7788

>T259497 WP_057085420.1 NZ_CP104920:3029341-3029835 [Dickeya solani]
MISAPEPLRAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMLLMVTLGDLVG
SLSI

Download         Length: 495 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10998.64 Da        Isoelectric Point: 9.8078

>AT259497 WP_057085421.1 NZ_CP104920:3029051-3029344 [Dickeya solani]
MPVTNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARVAAEEALIDQRIIMADPDAYQEFLARLDQVPEPN
AALRKTMQTPAPWEQKK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References