Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ataRT/DUF1778(antitoxin)
Location 2510927..2511669 Replicon chromosome
Accession NZ_CP104920
Organism Dickeya solani strain RNS 05.1.2A

Toxin (Protein)


Gene name ataT Uniprot ID E0SIC1
Locus tag RS71_RS11255 Protein ID WP_013316117.1
Coordinates 2511190..2511669 (+) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A3N0G0N1
Locus tag RS71_RS11250 Protein ID WP_019843650.1
Coordinates 2510927..2511199 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RS71_RS11240 2506495..2508858 - 2364 WP_057084318.1 class I SAM-dependent DNA methyltransferase -
RS71_RS11245 2509186..2510437 - 1252 Protein_2178 integrase arm-type DNA-binding domain-containing protein -
RS71_RS11250 2510927..2511199 + 273 WP_019843650.1 DUF1778 domain-containing protein Antitoxin
RS71_RS11255 2511190..2511669 + 480 WP_013316117.1 GNAT family N-acetyltransferase Toxin
RS71_RS11260 2511698..2512099 + 402 WP_057084319.1 hypothetical protein -
RS71_RS11265 2512244..2512540 - 297 WP_057084320.1 helix-turn-helix transcriptional regulator -
RS71_RS11270 2512668..2512890 + 223 Protein_2183 helix-turn-helix domain-containing protein -
RS71_RS11275 2512902..2513183 - 282 WP_057084321.1 Arm DNA-binding domain-containing protein -
RS71_RS11285 2513791..2514861 - 1071 WP_022631915.1 LPS export ABC transporter permease LptG -
RS71_RS11290 2514863..2515981 - 1119 WP_022631914.1 LPS export ABC transporter permease LptF -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2488007..2512561 24554


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-147)

Antitoxin

Vibrio phage ICP1, Orf50

(10-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17564.34 Da        Isoelectric Point: 9.5367

>T259495 WP_013316117.1 NZ_CP104920:2511190-2511669 [Dickeya solani]
VGITAPELLLPQHAVVDFHCSEPSLNEWLKRKALKNQTLGASRTFVVCEAGTQRVVGFYALASGSIQRQVAPGAFRRNMP
DPIPVLVLGRLAVDERYQRMGIGAGLLKDAVLRSRNVAQQVGNKALLVHALSDEAKAFYQYWGFVPSEIQEHTLLLSLW

Download         Length: 480 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10388.86 Da        Isoelectric Point: 4.6702

>AT259495 WP_019843650.1 NZ_CP104920:2510927-2511199 [Dickeya solani]
MRTETKEMPINIRAKASQRELIDVAAKLLSKSRTEFILDAACREAEDVLLDQRLFLVNDEQYDAFIQVLESPVTDNPRVN
ALLNRKSPWE

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3N0G158

Antitoxin

Source ID Structure
AlphaFold DB A0A3N0G0N1

References