Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 851749..852336 Replicon chromosome
Accession NZ_CP104917
Organism Avibacterium paragallinarum strain AP-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N8E87_RS04140 Protein ID WP_264246201.1
Coordinates 852040..852336 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8E87_RS04135 Protein ID WP_264246763.1
Coordinates 851749..852039 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E87_RS04115 (N8E87_04115) 846956..848068 + 1113 WP_264246193.1 porin -
N8E87_RS04120 (N8E87_04120) 848341..849417 + 1077 WP_264246195.1 porin -
N8E87_RS04125 (N8E87_04125) 849639..850712 + 1074 WP_264246197.1 porin -
N8E87_RS04130 (N8E87_04130) 850833..851558 - 726 WP_264246199.1 carboxy-S-adenosyl-L-methionine synthase CmoA -
N8E87_RS04135 (N8E87_04135) 851749..852039 + 291 WP_264246763.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N8E87_RS04140 (N8E87_04140) 852040..852336 + 297 WP_264246201.1 type II toxin-antitoxin system YafQ family toxin Toxin
N8E87_RS04145 (N8E87_04145) 852424..854202 + 1779 WP_264246203.1 aspartate--tRNA ligase -
N8E87_RS04150 (N8E87_04150) 854335..854667 + 333 WP_264246205.1 glucose-6-phosphate dehydrogenase -
N8E87_RS04155 (N8E87_04155) 854815..855762 + 948 WP_264246207.1 transposase -
N8E87_RS04160 (N8E87_04160) 855741..856022 + 282 WP_264246209.1 hypothetical protein -
N8E87_RS04165 (N8E87_04165) 856149..856538 + 390 WP_264246211.1 hypothetical protein -
N8E87_RS04170 (N8E87_04170) 856501..856959 + 459 WP_264246212.1 dihydroneopterin triphosphate diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(9-97)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-76)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11453.58 Da        Isoelectric Point: 8.7106

>T259487 WP_264246201.1 NZ_CP104917:852040-852336 [Avibacterium paragallinarum]
MNQSLPIKEIEMAKEFKRDLVQLAKKAPHLFVHPRYLEVMHCLTNGLALPAEYKNHPLKNNLKGYMDCHILNDLVLIYKI
EQQCLKLVRLNTHSEVFA

Download         Length: 297 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10643.29 Da        Isoelectric Point: 7.0088

>AT259487 WP_264246763.1 NZ_CP104917:851749-852039 [Avibacterium paragallinarum]
MMNNNAVVNFRLPQHLKTEAFEVIAQYGLTPSQVFNMFLTEIAATKAIPLSLNYLQPNAKTLAAMNEIESGTAERFSLDD
KTDLATLLQQIAKGKK

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References