Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 122598..123138 Replicon chromosome
Accession NZ_CP104917
Organism Avibacterium paragallinarum strain AP-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N8E87_RS00620 Protein ID WP_264245294.1
Coordinates 122848..123138 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8E87_RS00615 Protein ID WP_264245292.1
Coordinates 122598..122858 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E87_RS00605 (N8E87_00605) 119062..120063 + 1002 WP_264245287.1 site-specific integrase -
N8E87_RS00610 (N8E87_00610) 120965..122152 + 1188 WP_264245289.1 tyrosine-type recombinase/integrase -
N8E87_RS00615 (N8E87_00615) 122598..122858 + 261 WP_264245292.1 stability protein StbD Antitoxin
N8E87_RS00620 (N8E87_00620) 122848..123138 + 291 WP_264245294.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E87_RS00625 (N8E87_00625) 123866..124156 + 291 WP_017806817.1 co-chaperone GroES -
N8E87_RS00630 (N8E87_00630) 124235..125878 + 1644 WP_264245296.1 chaperonin GroEL -
N8E87_RS00635 (N8E87_00635) 126161..127108 - 948 WP_264245298.1 cysteine synthase A -
N8E87_RS00640 (N8E87_00640) 127264..128076 - 813 WP_264245300.1 sulfate transporter CysZ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - htpB 107468..136392 28924


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11444.39 Da        Isoelectric Point: 10.6525

>T259485 WP_264245294.1 NZ_CP104917:122848-123138 [Avibacterium paragallinarum]
MTYKLSFDKRALKEWYKLGDTLRQQFKAKLIERLENPHVLSDKLHGYQTLYKIKLRSAGYRLVYDVNDNEIRVIVLSVGK
RERLQAYKKALSRKAQ

Download         Length: 291 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9590.99 Da        Isoelectric Point: 4.1813

>AT259485 WP_264245292.1 NZ_CP104917:122598-122858 [Avibacterium paragallinarum]
MAIQQILTRHTASISDLKKNPMGIVSEGTEQEGAIAILNRNEPVFYCVTPRLFAVIQEILEDQELGELATQRLATLDPVE
VRLDDL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References