Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 113510..114050 Replicon chromosome
Accession NZ_CP104917
Organism Avibacterium paragallinarum strain AP-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N8E87_RS00565 Protein ID WP_110479397.1
Coordinates 113760..114050 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8E87_RS00560 Protein ID WP_110479398.1
Coordinates 113510..113770 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E87_RS00540 (N8E87_00540) 109635..110846 + 1212 WP_264245268.1 tyrosine-type recombinase/integrase -
N8E87_RS00545 (N8E87_00545) 111507..111713 + 207 WP_264245270.1 AlpA family phage regulatory protein -
N8E87_RS00550 (N8E87_00550) 111717..112394 + 678 WP_264245271.1 hypothetical protein -
N8E87_RS00555 (N8E87_00555) 112406..113371 + 966 WP_264245273.1 phage major capsid protein, P2 family -
N8E87_RS00560 (N8E87_00560) 113510..113770 + 261 WP_110479398.1 stability protein StbD Antitoxin
N8E87_RS00565 (N8E87_00565) 113760..114050 + 291 WP_110479397.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E87_RS00570 (N8E87_00570) 114092..115192 + 1101 WP_264245275.1 hypothetical protein -
N8E87_RS00575 (N8E87_00575) 115356..115571 + 216 WP_035688136.1 helix-turn-helix domain-containing protein -
N8E87_RS00580 (N8E87_00580) 115582..115887 + 306 WP_264245277.1 Lar family restriction alleviation protein -
N8E87_RS00585 (N8E87_00585) 115991..116557 + 567 WP_264245279.1 ash family protein -
N8E87_RS00590 (N8E87_00590) 116550..116819 + 270 WP_264245281.1 hypothetical protein -
N8E87_RS00595 (N8E87_00595) 116809..117048 + 240 WP_264245283.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - htpB 107468..136392 28924


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11418.36 Da        Isoelectric Point: 10.7313

>T259484 WP_110479397.1 NZ_CP104917:113760-114050 [Avibacterium paragallinarum]
MTYKLSFDKRALKEWHKLGDTLRQQFKAKLIERLENPHVLSDKLHGYQTLYKIKLRSAGYRLVYDVNDNEIRVIVLSVGK
RERLQAYKKALSRKAQ

Download         Length: 291 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9604.03 Da        Isoelectric Point: 4.3085

>AT259484 WP_110479398.1 NZ_CP104917:113510-113770 [Avibacterium paragallinarum]
MAIQQILTRHTASISDLKKNPMGIVSEGTEQEGAIAILNRNEPVFYCVNPRLFAVIQEILEDKELGELATQRLATLDPVE
VRLDDL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References