Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1911166..1911682 Replicon chromosome
Accession NZ_CP104914
Organism Avibacterium paragallinarum strain AG21-0333

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N8E86_RS08920 Protein ID WP_264255656.1
Coordinates 1911398..1911682 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N8E86_RS08915 Protein ID WP_264255655.1
Coordinates 1911166..1911408 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N8E86_RS08895 (N8E86_08895) 1906407..1907249 + 843 WP_039085670.1 ABC transporter permease -
N8E86_RS08900 (N8E86_08900) 1907273..1908358 + 1086 WP_264257055.1 extracellular solute-binding protein -
N8E86_RS08905 (N8E86_08905) 1908543..1909853 + 1311 WP_264255653.1 histidine-type phosphatase -
N8E86_RS08910 (N8E86_08910) 1909953..1911050 + 1098 WP_264255654.1 ROK family protein -
N8E86_RS08915 (N8E86_08915) 1911166..1911408 + 243 WP_264255655.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N8E86_RS08920 (N8E86_08920) 1911398..1911682 + 285 WP_264255656.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N8E86_RS08925 (N8E86_08925) 1911732..1912298 - 567 WP_103853318.1 elongation factor P -
N8E86_RS08930 (N8E86_08930) 1912333..1913346 + 1014 WP_264255657.1 EF-P beta-lysylation protein EpmB -
N8E86_RS08935 (N8E86_08935) 1913418..1914494 + 1077 WP_264255658.1 LysM-like peptidoglycan-binding domain-containing protein -
N8E86_RS08940 (N8E86_08940) 1914958..1915083 - 126 WP_261764806.1 hypothetical protein -
N8E86_RS08945 (N8E86_08945) 1915154..1916059 - 906 WP_026138508.1 recombination-associated protein RdgC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-57)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11197.07 Da        Isoelectric Point: 10.4599

>T259481 WP_264255656.1 NZ_CP104914:1911398-1911682 [Avibacterium paragallinarum]
MSYELVFDPRALKEWRKLGENIKAQFKKKLAEILRNPRIEANRLSHFPDCYKIKLRNAGYRLIYQVQDEQVVVFVVAIGK
RENNQAYKEAKTRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9202.64 Da        Isoelectric Point: 5.6725

>AT259481 WP_264255655.1 NZ_CP104914:1911166-1911408 [Avibacterium paragallinarum]
MATLNIRLDDELKQEAYAALQKMNLTPSEAVRLLFQYVAQNNKFPIQTVLVNDEDLELLKTVRHRLAHPEKGIKVSLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References