Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 36419..37072 Replicon chromosome
Accession NZ_CP104908
Organism Acinetobacter baumannii strain YZM-0314

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag N7297_RS00185 Protein ID WP_000607077.1
Coordinates 36419..36808 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag N7297_RS00190 Protein ID WP_001288210.1
Coordinates 36815..37072 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7297_RS00170 (N7297_00170) 31537..33732 - 2196 WP_001158906.1 TRAP transporter large permease subunit -
N7297_RS00175 (N7297_00175) 33920..34486 - 567 WP_000651538.1 rhombosortase -
N7297_RS00180 (N7297_00180) 34564..35649 - 1086 WP_000049106.1 hypothetical protein -
N7297_RS00185 (N7297_00185) 36419..36808 - 390 WP_000607077.1 membrane protein Toxin
N7297_RS00190 (N7297_00190) 36815..37072 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
N7297_RS00195 (N7297_00195) 37260..38432 + 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
N7297_RS00200 (N7297_00200) 38481..39971 - 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
N7297_RS00205 (N7297_00205) 40153..40530 - 378 WP_001216380.1 50S ribosomal protein L17 -
N7297_RS00210 (N7297_00210) 40549..41556 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T259466 WP_000607077.1 NZ_CP104908:c36808-36419 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT259466 WP_001288210.1 NZ_CP104908:c37072-36815 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References