Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 255403..256056 Replicon chromosome
Accession NZ_CP104907
Organism Acinetobacter baumannii strain Ab-3557

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag N7E62_RS01360 Protein ID WP_000607077.1
Coordinates 255667..256056 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag N7E62_RS01355 Protein ID WP_001288210.1
Coordinates 255403..255660 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E62_RS01335 (N7E62_01335) 250919..251926 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
N7E62_RS01340 (N7E62_01340) 251945..252322 + 378 WP_001216380.1 50S ribosomal protein L17 -
N7E62_RS01345 (N7E62_01345) 252504..253994 + 1491 WP_000415125.1 NAD(P)/FAD-dependent oxidoreductase -
N7E62_RS01350 (N7E62_01350) 254043..255215 - 1173 WP_001190542.1 acyl-CoA dehydrogenase family protein -
N7E62_RS01355 (N7E62_01355) 255403..255660 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
N7E62_RS01360 (N7E62_01360) 255667..256056 + 390 WP_000607077.1 membrane protein Toxin
N7E62_RS01365 (N7E62_01365) 256826..257911 + 1086 WP_000049106.1 hypothetical protein -
N7E62_RS01370 (N7E62_01370) 257989..258555 + 567 WP_000651538.1 rhombosortase -
N7E62_RS01375 (N7E62_01375) 258743..260938 + 2196 WP_001158906.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15552.88 Da        Isoelectric Point: 10.4313

>T259465 WP_000607077.1 NZ_CP104907:255667-256056 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT259465 WP_001288210.1 NZ_CP104907:255403-255660 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References