Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 128078..128670 Replicon chromosome
Accession NZ_CP104882
Organism Aggregatibacter actinomycetemcomitans strain IDHaas10a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N7761_RS00625 Protein ID WP_014167707.1
Coordinates 128371..128670 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N7761_RS00620 Protein ID WP_005568148.1
Coordinates 128078..128374 (-) Length 99 a.a.

Genomic Context


N7761_RS00605N7761_RS00615N7761_RS00630N7761_RS00640N7761_RS00650N7761_RS00590N7761_RS00595N7761_RS00600N7761_RS00610N7761_RS00620N7761_RS00625N7761_RS00635N7761_RS00645
Location: 125224..125703 (480 bp)
Type: Others
Protein ID: WP_262088995.1
Location: 127431..128045 (615 bp)
Type: Others
Protein ID: WP_005568146.1
Location: 128838..129140 (303 bp)
Type: Others
Protein ID: WP_005568150.1
Location: 129849..131291 (1443 bp)
Type: Others
Protein ID: WP_014167706.1
Location: 132177..133391 (1215 bp)
Type: Others
Protein ID: WP_014167705.1
Location: 123154..123951 (798 bp)
Type: Others
Protein ID: WP_005568139.1
Location: 123926..124387 (462 bp)
Type: Others
Protein ID: Protein_118
Location: 124360..125163 (804 bp)
Type: Others
Protein ID: WP_262088994.1
Location: 126007..127404 (1398 bp)
Type: Others
Protein ID: WP_005592819.1
Location: 128078..128374 (297 bp)
Type: Antitoxin
Protein ID: WP_005568148.1
Location: 128371..128670 (300 bp)
Type: Toxin
Protein ID: WP_014167707.1
Location: 129213..129689 (477 bp)
Type: Others
Protein ID: WP_005572298.1
Location: 131392..132048 (657 bp)
Type: Others
Protein ID: WP_005568155.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
N7761_RS00590 (N7761_00590)123154..123951-798WP_005568139.1ABC transporter permease-
N7761_RS00595 (N7761_00595)123926..124387-462Protein_118extracellular solute-binding protein-
N7761_RS00600 (N7761_00600)124360..125163-804WP_262088994.1oxidoreductase-
N7761_RS00605 (N7761_00605)125224..125703+480WP_262088995.1Cys-tRNA(Pro) deacylase-
N7761_RS00610 (N7761_00610)126007..127404-1398WP_005592819.1MATE family efflux transporter-
N7761_RS00615 (N7761_00615)127431..128045+615WP_005568146.1riboflavin synthase-
N7761_RS00620 (N7761_00620)128078..128374-297WP_005568148.1putative addiction module antidote proteinAntitoxin
N7761_RS00625 (N7761_00625)128371..128670-300WP_014167707.1type II toxin-antitoxin system RelE/ParE family toxinToxin
N7761_RS00630 (N7761_00630)128838..129140+303WP_005568150.1ribosome assembly RNA-binding protein YhbY-
N7761_RS00635 (N7761_00635)129213..129689-477WP_005572298.1transcription elongation factor GreA-
N7761_RS00640 (N7761_00640)129849..131291+1443WP_014167706.1serine-type D-Ala-D-Ala carboxypeptidase-
N7761_RS00645 (N7761_00645)131392..132048-657WP_005568155.1GTP cyclohydrolase I FolE-
N7761_RS00650 (N7761_00650)132177..133391+1215WP_014167705.1molybdopterin molybdotransferase MoeA-

Associated MGEs


Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(13-92)

Antitoxin

(5-91)


Sequences


Toxin        


Download         Length: 100 a.a.        Molecular weight: 11406.53 Da        Isoelectric Point: 10.6671

>T259454 WP_014167707.1 NZ_CP104882:c128670-128371 [Aggregatibacter actinomycetemcomitans]
MMIQIKTTFLFDEWLKKLKNLRAKAKINARIKRLQFGNFGDLKSVNDGIFEMRIDKGQGYRVYLKNQNGILVILLCGGDK
STQEKDIKKAKQLAQEMGL

Download         Length: 300 bp


Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10939.44 Da        Isoelectric Point: 4.4155

>AT259454 WP_005568148.1 NZ_CP104882:c128374-128078 [Aggregatibacter actinomycetemcomitans]
MSEQLKDFDPAEYLSTEEDIRLYLNEVLQENNIELILSALGDIARTRNMSQIARETGMSREGLYKALSGTGNPTFATVIK
VMKALNLQLQVQPSGYVS

Download         Length: 297 bp


Similar Proteins


Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

Loading, please wait
Source
ID
Structure
No matching records found


Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References