Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4647305..4648563 | Replicon | chromosome |
Accession | NZ_CP104869 | ||
Organism | Pseudomonas aeruginosa strain PALA8 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | PALA8_RS21410 | Protein ID | WP_269973425.1 |
Coordinates | 4647305..4648060 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PALA8_RS21415 | Protein ID | WP_003086329.1 |
Coordinates | 4648195..4648563 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PALA8_RS21400 (PALA8_04265) | 4642473..4645016 | + | 2544 | WP_003134033.1 | acyl-homoserine-lactone acylase QuiP | - |
PALA8_RS21405 (PALA8_04266) | 4645171..4646532 | - | 1362 | WP_003134034.1 | DNA recombination protein RmuC | - |
PALA8_RS21410 (PALA8_04267) | 4647305..4648060 | - | 756 | WP_269973425.1 | RES family NAD+ phosphorylase | Toxin |
PALA8_RS21415 (PALA8_04268) | 4648195..4648563 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PALA8_RS21420 (PALA8_04269) | 4648636..4649922 | - | 1287 | WP_003134035.1 | FAD-binding oxidoreductase | - |
PALA8_RS21425 | 4649978..4651568 | - | 1591 | Protein_4244 | aldehyde dehydrogenase family protein | - |
PALA8_RS21430 (PALA8_04272) | 4651647..4652123 | + | 477 | WP_003134036.1 | elongation factor GreAB | - |
PALA8_RS21435 | 4652126..4652401 | - | 276 | WP_023088486.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28164.28 Da Isoelectric Point: 8.0554
>T259423 WP_269973425.1 NZ_CP104869:c4648060-4647305 [Pseudomonas aeruginosa]
VSEIWRQCKGERHVRPLQGRLVRLVESQGQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHVRPLQGRLVRLVESQGQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT259423 WP_003086329.1 NZ_CP104869:c4648563-4648195 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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