Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | PanAT/DUF4065(antitoxin) |
Location | 284549..285504 | Replicon | chromosome |
Accession | NZ_CP104866 | ||
Organism | Pseudomonas aeruginosa strain PALA4 |
Toxin (Protein)
Gene name | panT | Uniprot ID | - |
Locus tag | PALA4_RS01315 | Protein ID | WP_170868726.1 |
Coordinates | 285178..285504 (+) | Length | 109 a.a. |
Antitoxin (Protein)
Gene name | panA | Uniprot ID | - |
Locus tag | PALA4_RS01310 | Protein ID | WP_023107584.1 |
Coordinates | 284549..285106 (+) | Length | 186 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PALA4_RS01285 (PALA4_00256) | 279606..279893 | - | 288 | WP_023443569.1 | hypothetical protein | - |
PALA4_RS01290 (PALA4_00257) | 279985..280461 | - | 477 | WP_009315008.1 | MarR family transcriptional regulator | - |
PALA4_RS01295 (PALA4_00258) | 280502..281992 | - | 1491 | WP_003111463.1 | UbiD family decarboxylase HudA | - |
PALA4_RS01300 (PALA4_00259) | 282126..282812 | - | 687 | WP_003106170.1 | YoaK family protein | - |
PALA4_RS01305 (PALA4_00260) | 282976..283908 | - | 933 | WP_023108709.1 | hypothetical protein | - |
PALA4_RS01310 (PALA4_00261) | 284549..285106 | + | 558 | WP_023107584.1 | Panacea domain-containing protein | Antitoxin |
PALA4_RS01315 (PALA4_00262) | 285178..285504 | + | 327 | WP_170868726.1 | hypothetical protein | Toxin |
PALA4_RS01325 (PALA4_00265) | 286949..288391 | - | 1443 | WP_003133043.1 | DUF2875 family protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 109 a.a. Molecular weight: 12366.33 Da Isoelectric Point: 8.6957
>T259397 WP_170868726.1 NZ_CP104866:285178-285504 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI
Download Length: 327 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 21377.14 Da Isoelectric Point: 5.8950
>AT259397 WP_023107584.1 NZ_CP104866:284549-285106 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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