Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 284549..285504 Replicon chromosome
Accession NZ_CP104866
Organism Pseudomonas aeruginosa strain PALA4

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag PALA4_RS01315 Protein ID WP_170868726.1
Coordinates 285178..285504 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag PALA4_RS01310 Protein ID WP_023107584.1
Coordinates 284549..285106 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PALA4_RS01285 (PALA4_00256) 279606..279893 - 288 WP_023443569.1 hypothetical protein -
PALA4_RS01290 (PALA4_00257) 279985..280461 - 477 WP_009315008.1 MarR family transcriptional regulator -
PALA4_RS01295 (PALA4_00258) 280502..281992 - 1491 WP_003111463.1 UbiD family decarboxylase HudA -
PALA4_RS01300 (PALA4_00259) 282126..282812 - 687 WP_003106170.1 YoaK family protein -
PALA4_RS01305 (PALA4_00260) 282976..283908 - 933 WP_023108709.1 hypothetical protein -
PALA4_RS01310 (PALA4_00261) 284549..285106 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
PALA4_RS01315 (PALA4_00262) 285178..285504 + 327 WP_170868726.1 hypothetical protein Toxin
PALA4_RS01325 (PALA4_00265) 286949..288391 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12366.33 Da        Isoelectric Point: 8.6957

>T259397 WP_170868726.1 NZ_CP104866:285178-285504 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT259397 WP_023107584.1 NZ_CP104866:284549-285106 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References