Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /Xre(antitoxin) |
Location | 4265089..4266347 | Replicon | chromosome |
Accession | NZ_CP104865 | ||
Organism | Pseudomonas aeruginosa strain PALA2 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | PALA2_RS19770 | Protein ID | WP_003163133.1 |
Coordinates | 4265089..4265844 (-) | Length | 252 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | V6AJU7 |
Locus tag | PALA2_RS19775 | Protein ID | WP_003086329.1 |
Coordinates | 4265979..4266347 (-) | Length | 123 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PALA2_RS19760 (PALA2_03936) | 4260263..4262806 | + | 2544 | WP_003140632.1 | acyl-homoserine-lactone acylase QuiP | - |
PALA2_RS19765 (PALA2_03937) | 4262961..4264322 | - | 1362 | WP_003081943.1 | DNA recombination protein RmuC | - |
PALA2_RS19770 (PALA2_03938) | 4265089..4265844 | - | 756 | WP_003163133.1 | RES family NAD+ phosphorylase | Toxin |
PALA2_RS19775 (PALA2_03939) | 4265979..4266347 | - | 369 | WP_003086329.1 | DUF2384 domain-containing protein | Antitoxin |
PALA2_RS19780 (PALA2_03940) | 4266420..4267706 | - | 1287 | WP_023096923.1 | FAD-binding oxidoreductase | - |
PALA2_RS19785 (PALA2_03941) | 4267762..4269351 | - | 1590 | WP_003125055.1 | aldehyde dehydrogenase family protein | - |
PALA2_RS19790 (PALA2_03942) | 4269430..4269906 | + | 477 | WP_003112531.1 | hypothetical protein | - |
PALA2_RS19795 | 4269909..4270184 | - | 276 | WP_169057979.1 | zinc ribbon domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 252 a.a. Molecular weight: 28250.37 Da Isoelectric Point: 7.7294
>T259393 WP_003163133.1 NZ_CP104865:c4265844-4265089 [Pseudomonas aeruginosa]
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
VSEIWRQCKGERHIRPLQGRLVRLVESQEQVATLQLVDTLEEQALLEELLESSKPPVPADAEPLHYLLKTPFRYPPLRWG
SRFGRRHEPSLFYAALKLETAMAESAYYRCVLWSGMAVPPPSGRILSEHASFEAGWKVERGIRLQAPPFSDHEAALTDIA
DYRAPQELGSAMRSAGVQAFEYRSARCPERGCNVALFTPAAFTEKRPRNLTPWLCETTAGYVAFKPAHVPGSPKIFSWEL
FLVDGKLPHPA
Download Length: 756 bp
Antitoxin
Download Length: 123 a.a. Molecular weight: 13367.63 Da Isoelectric Point: 9.9874
>AT259393 WP_003086329.1 NZ_CP104865:c4266347-4265979 [Pseudomonas aeruginosa]
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
MSALIKERPSADAVLAKAVLAAREQLGLTQLELAGIVGVDRSAISRWKTQGLRVDSKTGELALLLVRVYRALYALFGGQQ
EDMRHFLRTPNHHLAGEPLALMGQVQGLVHVLEYLDAIRGKV
Download Length: 369 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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