Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 918409..919069 Replicon chromosome
Accession NZ_CP104858
Organism Salmonella sp. 3C

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag N7E69_RS04315 Protein ID WP_000244756.1
Coordinates 918409..918822 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag N7E69_RS04320 Protein ID WP_000351186.1
Coordinates 918803..919069 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E69_RS04295 (914350) 914350..916083 - 1734 WP_000813387.1 single-stranded-DNA-specific exonuclease RecJ -
N7E69_RS04300 (916089) 916089..916802 - 714 WP_000745614.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N7E69_RS04305 (916826) 916826..917722 - 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
N7E69_RS04310 (917835) 917835..918356 + 522 WP_001055885.1 flavodoxin FldB -
N7E69_RS04315 (918409) 918409..918822 - 414 WP_000244756.1 protein YgfX Toxin
N7E69_RS04320 (918803) 918803..919069 - 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
N7E69_RS04325 (919319) 919319..920299 + 981 WP_000874174.1 tRNA-modifying protein YgfZ -
N7E69_RS04330 (920415) 920415..921074 - 660 WP_000250289.1 hemolysin III family protein -
N7E69_RS04335 (921236) 921236..921550 - 315 WP_001182980.1 N(4)-acetylcytidine aminohydrolase -
N7E69_RS04340 (921705) 921705..923138 + 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T259363 WP_000244756.1 NZ_CP104858:c918822-918409 [Salmonella sp. 3C]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT259363 WP_000351186.1 NZ_CP104858:c919069-918803 [Salmonella sp. 3C]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References