Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 3232134..3232699 Replicon chromosome
Accession NZ_CP104794
Organism Streptomyces sp. FZ201

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag N6J21_RS14370 Protein ID WP_250744431.1
Coordinates 3232134..3232502 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag N6J21_RS14375 Protein ID WP_093721371.1
Coordinates 3232502..3232699 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6J21_RS14350 3227490..3228449 + 960 WP_093721367.1 glycine betaine ABC transporter substrate-binding protein -
N6J21_RS14355 3228465..3229256 - 792 WP_093721368.1 S16 family serine protease -
N6J21_RS14360 3229301..3229942 - 642 WP_093721413.1 helix-turn-helix domain-containing protein -
N6J21_RS14365 3230233..3232026 - 1794 WP_093721369.1 DEAD/DEAH box helicase -
N6J21_RS14370 3232134..3232502 - 369 WP_250744431.1 Fic family protein Toxin
N6J21_RS14375 3232502..3232699 - 198 WP_093721371.1 hypothetical protein Antitoxin
N6J21_RS14380 3232732..3234177 - 1446 WP_261718512.1 MFS transporter -
N6J21_RS14385 3234266..3234787 - 522 WP_093721373.1 SUKH-4 family immunity protein -
N6J21_RS14390 3234859..3237171 - 2313 WP_093721374.1 molybdopterin-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(11-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13748.58 Da        Isoelectric Point: 4.8625

>T259188 WP_250744431.1 NZ_CP104794:c3232502-3232134 [Streptomyces sp. FZ201]
MHYLTLPELLHLAKRLGADEVRDYGLLDSALARPQSSVFGQDAYPDVWQKAAALMESLARNHSLVDGNKRIAWYATWVFL
HLNGHPLDAEFDVDEAEQFVLDVCQGDLDVTKIAAQLPRFAR

Download         Length: 369 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7222.15 Da        Isoelectric Point: 6.4639

>AT259188 WP_093721371.1 NZ_CP104794:c3232699-3232502 [Streptomyces sp. FZ201]
MAGLNLRFTEEELNALRERAAAEGRSMQAFAHDAVIAAINERSRLFNEAAEHVLKASAELNRRLA

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References