259154

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) BrnTA/BrnT-BrnA
Location 270..8736 Replicon plasmid punamed2
Accession NZ_CP104785
Organism Acinetobacter baumannii strain Ab-3556

Toxin (Protein)


Gene name brnT Uniprot ID A0A3G6Z3M6
Locus tag N7E56_RS00005 Protein ID WP_000438826.1
Coordinates 8736..283 (+) Length -2817.3333333333 a.a.

Antitoxin (Protein)


Gene name brnA Uniprot ID N9M5I3
Locus tag N7E56_RS00010 Protein ID WP_001983304.1
Coordinates 270..584 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E56_RS00010 270..584 + 315 WP_001983304.1 BrnA antitoxin family protein Antitoxin
N7E56_RS00015 712..3123 + 2412 WP_000932953.1 TonB-dependent receptor ZnuD2 -
N7E56_RS00020 3429..3888 + 460 Protein_3 DIP1984 family protein -
N7E56_RS00025 4211..4384 - 174 WP_001282484.1 hypothetical protein -
N7E56_RS00030 4384..4755 - 372 WP_000504218.1 hypothetical protein -
N7E56_RS00035 5965..6922 + 958 Protein_6 replication initiation protein RepM -
N7E56_RS00040 6915..7492 + 578 Protein_7 helix-turn-helix domain-containing protein -
N7E56_RS00045 7512..7655 + 144 WP_261630927.1 hypothetical protein -
N7E56_RS00050 7828..8351 - 524 Protein_9 sel1 repeat family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..8740 8740


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(41-96)


Sequences

Toxin        


Download         Length: -2817.3333333333 a.a.        Molecular weight: Da        Isoelectric Point:

>T259154 WP_000438826.1 NZ_CP104785:8736-283 [Acinetobacter baumannii]

Download         Length: -8452 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 12208.84 Da        Isoelectric Point: 7.2026

>AT259154 WP_001983304.1 NZ_CP104785:270-584 [Acinetobacter baumannii]
MSMVRYSHKELNEKFGEKQDAEIQRLLAKGTVPDDQLDLSDIPEITDWSNAVRQNQFYRPVKQQTSIRLDADVLAWFKAQ
GKGYQTRMNEILRDAMLKELKNHQ

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G6Z3M6

Antitoxin

Source ID Structure
AlphaFold DB N9M5I3

References