Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Xre-MNT/HTH_26(antitoxin)
Location 1102637..1103745 Replicon chromosome
Accession NZ_CP104764
Organism Enterococcus raffinosus strain Er676

Toxin (Protein)


Gene name MNTss Uniprot ID -
Locus tag N7K39_RS05635 Protein ID WP_161999060.1
Coordinates 1102876..1103745 (+) Length 290 a.a.

Antitoxin (Protein)


Gene name Xress Uniprot ID -
Locus tag N7K39_RS05630 Protein ID WP_000205227.1
Coordinates 1102637..1102861 (+) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7K39_RS05610 (N7K39_05610) 1098873..1099691 - 819 WP_261660980.1 ABC transporter permease -
N7K39_RS05615 (N7K39_05615) 1100016..1100513 + 498 WP_002327635.1 DNA recombinase -
N7K39_RS05620 (N7K39_05620) 1100514..1100930 + 417 WP_000323438.1 recombinase -
N7K39_RS05625 (N7K39_05625) 1100950..1102494 + 1545 WP_002390960.1 recombinase family protein -
N7K39_RS05630 (N7K39_05630) 1102637..1102861 + 225 WP_000205227.1 helix-turn-helix transcriptional regulator Antitoxin
N7K39_RS05635 (N7K39_05635) 1102876..1103745 + 870 WP_161999060.1 nucleotidyltransferase domain-containing protein Toxin
N7K39_RS05640 (N7K39_05640) 1103726..1104460 + 735 WP_000662263.1 class I SAM-dependent methyltransferase -
N7K39_RS05645 (N7K39_05645) 1104493..1105356 + 864 WP_002294505.1 aminoglycoside nucleotidyltransferase ANT(6)-Ia -
N7K39_RS05650 (N7K39_05650) 1105400..1105927 + 528 WP_002294507.1 phosphoribosyltransferase family protein -
N7K39_RS05655 (N7K39_05655) 1106155..1107474 + 1320 WP_159373775.1 IS1380-like element ISSsu5 family transposase -
N7K39_RS05660 (N7K39_05660) 1107674..1108432 - 759 WP_261660981.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Polymerase, nucleotidyl transferase domain

(12-111)

Antitoxin

Cro/C1-type helix-turn-helix domain

(4-57)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32930.56 Da        Isoelectric Point: 4.8781

>T259136 WP_161999060.1 NZ_CP104764:1102876-1103745 [Enterococcus raffinosus]
MVGNVIQIVTEKLSSLPFIEGIVLGGSRARGTHTENSDIDIGIYYNSDSFDLTAINQIATELDDKNRNNLVVPPGAWGDW
INGGGWLFINGYHVDLILRDIKRVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
PTALKKSLMNFFIFEAEFSLMFVKANAGVEDKYYIAGHVFRIISCLNQVLFACNNAYCINEKKAIKLLETFEYKTEKYAE
RVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINNFLNEESSDERKQI

Download         Length: 870 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8365.68 Da        Isoelectric Point: 4.5510

>AT259136 WP_000205227.1 NZ_CP104764:1102637-1102861 [Enterococcus raffinosus]
MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLDELKAIADVLGVKFVQAFILPDGEEIKISNE

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References