259126

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 2836060..2836679 Replicon chromosome
Accession NZ_CP104758
Organism Kalamiella piersonii strain GABEKP28

Toxin (Protein)


Gene name Hha Uniprot ID -
Locus tag N5580_RS13590 Protein ID WP_120451305.1
Coordinates 2836461..2836679 (+) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag N5580_RS13585 Protein ID WP_120451306.1
Coordinates 2836060..2836437 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5580_RS13555 (2832368) 2832368..2832619 + 252 WP_120451311.1 type B 50S ribosomal protein L31 -
N5580_RS13560 (2832631) 2832631..2832771 + 141 WP_071997379.1 type B 50S ribosomal protein L36 -
N5580_RS13565 (2832813) 2832813..2833691 - 879 WP_120451310.1 metal ABC transporter substrate-binding protein -
N5580_RS13570 (2833704) 2833704..2834543 - 840 WP_269949393.1 metal ABC transporter permease -
N5580_RS13575 (2834540) 2834540..2835205 - 666 WP_269950357.1 ABC transporter ATP-binding protein -
N5580_RS13580 (2835558) 2835558..2835911 + 354 WP_269949394.1 hypothetical protein -
N5580_RS13585 (2836060) 2836060..2836437 + 378 WP_120451306.1 Hha toxicity modulator TomB Antitoxin
N5580_RS13590 (2836461) 2836461..2836679 + 219 WP_120451305.1 HHA domain-containing protein Toxin
N5580_RS13600 (2837066) 2837066..2837377 + 312 WP_120451304.1 MGMT family protein -
N5580_RS13605 (2837410) 2837410..2837967 - 558 WP_269949395.1 YbaY family lipoprotein -
N5580_RS13610 (2838157) 2838157..2839020 + 864 WP_120451302.1 acyl-CoA thioesterase II -
N5580_RS13615 (2839139) 2839139..2840431 - 1293 WP_120451301.1 ammonium transporter AmtB -
N5580_RS13620 (2840465) 2840465..2840803 - 339 WP_033752690.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8601.92 Da        Isoelectric Point: 8.9007

>T259126 WP_120451305.1 NZ_CP104758:2836461-2836679 [Kalamiella piersonii]
MNDKTLTKTDYLMRLRRCRSIDTLERVIEKNKYELSDDELAVFYSAADHRLAELTMNKLYDKVPGSVWKFVR

Download         Length: 219 bp

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14763.31 Da        Isoelectric Point: 4.3276

>AT259126 WP_120451306.1 NZ_CP104758:2836060-2836437 [Kalamiella piersonii]
MDEYSPKRHDIAQLKFLCENLFDESMATLTDSHHGWVNDPTSENNLQLNDLIEHIASFTMNYKIKHAEDEDLITQIDDYL
DDTFMLFTNYGINAQDLNRWQRSARRLFNLFSEECAYLQQPSHSI

Download         Length: 378 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References