Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 47899..48598 Replicon chromosome
Accession NZ_CP104758
Organism Kalamiella piersonii strain GABEKP28

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N5580_RS00215 Protein ID WP_269949705.1
Coordinates 47899..48288 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag N5580_RS00220 Protein ID WP_126690121.1
Coordinates 48281..48598 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5580_RS00200 (43534) 43534..44529 - 996 WP_120457791.1 acyltransferase -
N5580_RS00205 (44722) 44722..45633 + 912 WP_120457793.1 glycine--tRNA ligase subunit alpha -
N5580_RS00210 (45643) 45643..47712 + 2070 WP_269949704.1 glycine--tRNA ligase subunit beta -
N5580_RS00215 (47899) 47899..48288 + 390 WP_269949705.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5580_RS00220 (48281) 48281..48598 + 318 WP_126690121.1 helix-turn-helix domain-containing protein Antitoxin
N5580_RS00225 (48783) 48783..49394 - 612 WP_269949706.1 glutathione S-transferase -
N5580_RS00230 (49421) 49421..50347 - 927 WP_126690119.1 formate dehydrogenase accessory protein FdhE -
N5580_RS00235 (50347) 50347..50988 - 642 WP_269949707.1 formate dehydrogenase cytochrome b556 subunit -
N5580_RS00240 (50985) 50985..51869 - 885 WP_126690117.1 formate dehydrogenase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-125)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-92)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15046.29 Da        Isoelectric Point: 5.8545

>T259121 WP_269949705.1 NZ_CP104758:47899-48288 [Kalamiella piersonii]
MGIYLTPEFDEERRRLGITDKVICKTARKVYSGLKGDQLGKFTYKRRIALSKVGERGGARSIVFFNEGEHLYFFYLYAKS
ELSKKKGKEIEDAEIEIFCDIASDFIEMDDARIKHLLEEKELFEVKCDE

Download         Length: 390 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12036.94 Da        Isoelectric Point: 10.3129

>AT259121 WP_126690121.1 NZ_CP104758:48281-48598 [Kalamiella piersonii]
MSDDLKKIYAMARRYNKHGVVKDETLKTIETRIKAADIPEVRPMTGEEIKEVRQRWKLSQSALARTTGMSVESVSKWERG
ESKPNQAVLRIINMISDKGPEIFMS

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References