Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1752298..1752851 Replicon chromosome
Accession NZ_CP104757
Organism Pectobacterium aroidearum strain QJ021

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag N5056_RS07715 Protein ID WP_181829556.1
Coordinates 1752537..1752851 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID C6CEY1
Locus tag N5056_RS07710 Protein ID WP_012769207.1
Coordinates 1752298..1752534 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5056_RS07695 (N5056_07695) 1747388..1748704 - 1317 WP_181829554.1 ATP-binding protein -
N5056_RS07700 (N5056_07700) 1748708..1751017 - 2310 WP_181829555.1 TerB N-terminal domain-containing protein -
N5056_RS07705 (N5056_07705) 1751780..1752115 + 336 Protein_1508 ArdC family protein -
N5056_RS07710 (N5056_07710) 1752298..1752534 + 237 WP_012769207.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
N5056_RS07715 (N5056_07715) 1752537..1752851 + 315 WP_181829556.1 CcdB family protein Toxin
N5056_RS07720 (N5056_07720) 1752885..1752986 - 102 Protein_1511 mobilization protein mobC -
N5056_RS07725 (N5056_07725) 1752986..1753150 - 165 Protein_1512 Arm DNA-binding domain-containing protein -
N5056_RS07735 (N5056_07735) 1753511..1754308 - 798 WP_181829557.1 DgsA anti-repressor MtfA -
N5056_RS07745 (N5056_07745) 1754550..1754936 - 387 WP_015839750.1 lysozyme inhibitor LprI family protein -
N5056_RS07750 (N5056_07750) 1755112..1755279 + 168 WP_015839751.1 YqaE/Pmp3 family membrane protein -
N5056_RS07755 (N5056_07755) 1755364..1756785 - 1422 WP_181829558.1 DASS family sodium-coupled anion symporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11551.48 Da        Isoelectric Point: 7.9859

>T259118 WP_181829556.1 NZ_CP104757:1752537-1752851 [Pectobacterium aroidearum]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYTVMTHELASIPVQALG
AVFCDASQYRSQVKAAIDFLIDGF

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9013.03 Da        Isoelectric Point: 6.4631

>AT259118 WP_012769207.1 NZ_CP104757:1752298-1752534 [Pectobacterium aroidearum]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLSTALDAELRRHEAKKWQEENREAIDALNRFHDENGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E4H0

References