Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 747566..748226 Replicon chromosome
Accession NZ_CP104757
Organism Pectobacterium aroidearum strain QJ021

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag N5056_RS03365 Protein ID WP_043881709.1
Coordinates 747852..748226 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID C6D8Y5
Locus tag N5056_RS03360 Protein ID WP_012773340.1
Coordinates 747566..747832 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5056_RS03340 (N5056_03340) 743558..744562 - 1005 WP_181829660.1 LacI family DNA-binding transcriptional regulator -
N5056_RS03345 (N5056_03345) 744606..745214 - 609 WP_181829659.1 HD domain-containing protein -
N5056_RS03350 (N5056_03350) 745627..746274 + 648 WP_181829658.1 hemolysin III family protein -
N5056_RS03355 (N5056_03355) 746329..747330 - 1002 WP_181829657.1 tRNA-modifying protein YgfZ -
N5056_RS03360 (N5056_03360) 747566..747832 + 267 WP_012773340.1 FAD assembly factor SdhE Antitoxin
N5056_RS03365 (N5056_03365) 747852..748226 + 375 WP_043881709.1 protein YgfX Toxin
N5056_RS03370 (N5056_03370) 748296..749231 + 936 WP_181829656.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
N5056_RS03375 (N5056_03375) 749277..749600 - 324 WP_180777498.1 hypothetical protein -
N5056_RS03380 (N5056_03380) 749629..750147 - 519 WP_012773344.1 flavodoxin FldB -
N5056_RS03385 (N5056_03385) 750310..751638 - 1329 WP_012773346.1 MFS transporter -
N5056_RS03390 (N5056_03390) 751950..752849 + 900 WP_012773347.1 site-specific tyrosine recombinase XerD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-119)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 14673.34 Da        Isoelectric Point: 10.6585

>T259116 WP_043881709.1 NZ_CP104757:747852-748226 [Pectobacterium aroidearum]
MQLLSLIVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GVLLSLQAVNGKDRQQLWLASDSMGDDEWRHLRQLLLQQKNWAR

Download         Length: 375 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10465.94 Da        Isoelectric Point: 6.2223

>AT259116 WP_012773340.1 NZ_CP104757:747566-747832 [Pectobacterium aroidearum]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E501

References