Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 197884..198518 Replicon chromosome
Accession NZ_CP104757
Organism Pectobacterium aroidearum strain QJ021

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag N5056_RS00910 Protein ID WP_181830242.1
Coordinates 197884..198159 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag N5056_RS00915 Protein ID WP_181830203.1
Coordinates 198156..198518 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5056_RS00875 (N5056_00875) 192972..193037 - 66 WP_228925434.1 GpE family phage tail protein -
N5056_RS00880 (N5056_00880) 193121..193441 - 321 WP_039490576.1 phage tail assembly protein -
N5056_RS00885 (N5056_00885) 193448..193963 - 516 WP_181838257.1 phage major tail tube protein -
N5056_RS00890 (N5056_00890) 193974..195167 - 1194 WP_181838256.1 phage tail sheath protein -
N5056_RS00895 (N5056_00895) 195324..196457 + 1134 WP_181838255.1 phage late control D family protein -
N5056_RS00900 (N5056_00900) 196508..196750 + 243 WP_015840867.1 ogr/Delta-like zinc finger family protein -
N5056_RS00905 (N5056_00905) 196890..197633 + 744 WP_181838254.1 type VI secretion system-associated protein TagO -
N5056_RS00910 (N5056_00910) 197884..198159 + 276 WP_181830242.1 type II toxin-antitoxin system HicA family toxin Toxin
N5056_RS00915 (N5056_00915) 198156..198518 + 363 WP_181830203.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
N5056_RS00920 (N5056_00920) 198893..200080 + 1188 WP_180779137.1 sugar transporter -
N5056_RS00925 (N5056_00925) 200124..201026 + 903 WP_181830202.1 CDF family cation-efflux transporter FieF -
N5056_RS00930 (N5056_00930) 201234..202196 + 963 WP_012772882.1 6-phosphofructokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(30-80)

Antitoxin

Uncharacterised protein family HicB

(61-113)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10037.61 Da        Isoelectric Point: 11.1875

>T259112 WP_181830242.1 NZ_CP104757:197884-198159 [Pectobacterium aroidearum]
MQGKIASLRKKQRETLSQIFKTPVLSGVKWSNVESLITALGGEIKDGSGSRVRFLLNGSIARFHRPHPSPDTDKGALVNL
REWLESIGVKP

Download         Length: 276 bp

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13577.41 Da        Isoelectric Point: 4.4981

>AT259112 WP_181830203.1 NZ_CP104757:198156-198518 [Pectobacterium aroidearum]
MTKALNTPNTMVVSGQPAIISYVPEIGMFRGKFIGLSGYCDFVADSINGLRNEGEISLREYLEDCQENGIEPYEREEKVK
TFTLRYPESFGERLTIAAAERQISVNTFIVETLNERMKQA

Download         Length: 363 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References