Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 4171848..4172398 Replicon chromosome
Accession NZ_CP104755
Organism Shewanella putrefaciens strain 4H

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag N5094_RS18440 Protein ID WP_011918510.1
Coordinates 4172099..4172398 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag N5094_RS18435 Protein ID WP_011918511.1
Coordinates 4171848..4172090 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5094_RS18410 (N5094_18410) 4166958..4168157 + 1200 WP_261762122.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -
N5094_RS18415 (N5094_18415) 4168162..4168695 + 534 WP_025008034.1 hotdog family protein -
N5094_RS18420 (N5094_18420) 4168808..4169533 + 726 WP_248069540.1 3-ketoacyl-ACP reductase FabG2 -
N5094_RS18425 (N5094_18425) 4169534..4170793 + 1260 WP_248069538.1 beta-ketoacyl-ACP synthase -
N5094_RS18430 (N5094_18430) 4170825..4171568 + 744 WP_248069536.1 hypothetical protein -
N5094_RS18435 (N5094_18435) 4171848..4172090 + 243 WP_011918511.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N5094_RS18440 (N5094_18440) 4172099..4172398 + 300 WP_011918510.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5094_RS18445 (N5094_18445) 4172928..4173641 - 714 WP_014609649.1 hypothetical protein -
N5094_RS18450 (N5094_18450) 4174001..4174477 + 477 WP_261762123.1 GNAT family N-acetyltransferase -
N5094_RS18455 (N5094_18455) 4174529..4175716 - 1188 WP_115016493.1 benzoate/H(+) symporter BenE family transporter -
N5094_RS18460 (N5094_18460) 4175880..4176446 + 567 WP_014609647.1 XRE family transcriptional regulator -
N5094_RS18465 (N5094_18465) 4176583..4177179 - 597 WP_011787674.1 FMN-dependent NADH-azoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-64)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11598.24 Da        Isoelectric Point: 8.8270

>T259109 WP_011918510.1 NZ_CP104755:4172099-4172398 [Shewanella putrefaciens]
MNNKRYKLSRLSQTHLQQIKDYTLQHFSESQWHKYKESLISGLQMLADNPGLGRSCEDIYPNGFYFPIAKHTAYFTKEDD
FILIVALLGQPQLPQNHLK

Download         Length: 300 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8936.14 Da        Isoelectric Point: 5.0758

>AT259109 WP_011918511.1 NZ_CP104755:4171848-4172090 [Shewanella putrefaciens]
VQTLTANEAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References