Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3288243..3288912 Replicon chromosome
Accession NZ_CP104755
Organism Shewanella putrefaciens strain 4H

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag N5094_RS14500 Protein ID WP_261761863.1
Coordinates 3288243..3288683 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag N5094_RS14505 Protein ID WP_014610118.1
Coordinates 3288664..3288912 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5094_RS14475 (N5094_14475) 3283749..3284222 - 474 WP_261761862.1 SoxR reducing system RseC family protein -
N5094_RS14480 (N5094_14480) 3284233..3285165 - 933 WP_011790278.1 MucB/RseB C-terminal domain-containing protein -
N5094_RS14485 (N5094_14485) 3285178..3285798 - 621 WP_011790279.1 anti sigma-E factor RseA C-terminal domain-containing protein -
N5094_RS14490 (N5094_14490) 3285825..3286403 - 579 WP_011790280.1 RNA polymerase sigma factor RpoE -
N5094_RS14495 (N5094_14495) 3286593..3288206 + 1614 WP_248065600.1 L-aspartate oxidase -
N5094_RS14500 (N5094_14500) 3288243..3288683 - 441 WP_261761863.1 hypothetical protein Toxin
N5094_RS14505 (N5094_14505) 3288664..3288912 - 249 WP_014610118.1 succinate dehydrogenase assembly factor 2 Antitoxin
N5094_RS14510 (N5094_14510) 3288998..3289906 - 909 WP_011790284.1 transcriptional activator NhaR -
N5094_RS14515 (N5094_14515) 3290014..3290400 - 387 WP_011790285.1 hypothetical protein -
N5094_RS14520 (N5094_14520) 3290403..3291572 - 1170 WP_011790286.1 Na+/H+ antiporter NhaA -
N5094_RS14525 (N5094_14525) 3291689..3292483 - 795 WP_011790287.1 thymidylate synthase -
N5094_RS14530 (N5094_14530) 3292483..3293289 - 807 WP_115015839.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(6-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-78)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17341.58 Da        Isoelectric Point: 9.2750

>T259108 WP_261761863.1 NZ_CP104755:c3288683-3288243 [Shewanella putrefaciens]
VEEQHHSFSVKASFDQRLSLVVFMCVCSSSFLIWPYTEHWLVALLRLGLFLLSVSFLIWQLWRLKDWRLSFMLNGKGDGR
LSTGEHFRILRRTWVTPFVCMIYIDVEEKTRLVLLWADMFTGVDYRHLCRLLLKAKMLQAKSQVEI

Download         Length: 441 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9545.15 Da        Isoelectric Point: 4.5994

>AT259108 WP_014610118.1 NZ_CP104755:c3288912-3288664 [Shewanella putrefaciens]
MELMNIARVRWACRRGMLELDVLFQPFVENIYQDLSDIDKASFIRLLECEDPELFAWFMGHEACPDAELARMVVKVRGRA
AP

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References