Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 2485992..2486551 Replicon chromosome
Accession NZ_CP104755
Organism Shewanella putrefaciens strain 4H

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag N5094_RS10945 Protein ID WP_172591132.1
Coordinates 2485992..2486381 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag N5094_RS10950 Protein ID WP_172591131.1
Coordinates 2486381..2486551 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5094_RS10935 (N5094_10935) 2482680..2483003 + 324 WP_261761631.1 helix-turn-helix domain-containing protein -
N5094_RS10940 (N5094_10940) 2483150..2485867 + 2718 WP_261761632.1 phage/plasmid primase, P4 family -
N5094_RS10945 (N5094_10945) 2485992..2486381 - 390 WP_172591132.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
N5094_RS10950 (N5094_10950) 2486381..2486551 - 171 WP_172591131.1 acetyltransferase Antitoxin
N5094_RS10955 (N5094_10955) 2486677..2488494 - 1818 WP_261761633.1 site-specific integrase -
N5094_RS10965 (N5094_10965) 2488934..2490928 - 1995 WP_011919219.1 nitrate- and nitrite sensing domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(1-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14212.28 Da        Isoelectric Point: 3.9777

>T259107 WP_172591132.1 NZ_CP104755:c2486381-2485992 [Shewanella putrefaciens]
MDIICFPFERVVEINALILSTEPGMKGAVDIPKLQGALSRIDNAIVYQGLDDVFEIAAKYTACIAVSHACPDANKRTGLA
VALEYLSLNDYEITEDNELLANAIRDLVLQEITETDFADILYAQYLKGL

Download         Length: 390 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6414.58 Da        Isoelectric Point: 11.0174

>AT259107 WP_172591131.1 NZ_CP104755:c2486551-2486381 [Shewanella putrefaciens]
MNRKLEVYGVQVVTRPKIKATKQLDLSGDFGRQIVKSETKLALRTHPKTFQKLADM

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References