259105

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 1546818..1547649 Replicon chromosome
Accession NZ_CP104755
Organism Shewanella putrefaciens strain 4H

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag N5094_RS06765 Protein ID WP_088585313.1
Coordinates 1546818..1547234 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag N5094_RS06770 Protein ID WP_088585314.1
Coordinates 1547227..1547649 (-) Length 141 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5094_RS06730 (N5094_06730) 1541877..1543487 - 1611 WP_011787758.1 IS1634-like element ISSpu7 family transposase -
N5094_RS06735 (N5094_06735) 1543695..1544039 - 345 WP_261762689.1 IS66 family insertion sequence element accessory protein TnpB -
N5094_RS06740 (N5094_06740) 1544036..1544335 - 300 WP_088585869.1 hypothetical protein -
N5094_RS06745 (N5094_06745) 1544465..1545817 + 1353 WP_261762690.1 phosphoglucosamine mutase -
N5094_RS06750 (N5094_06750) 1546027..1546170 - 144 WP_261762691.1 hypothetical protein -
N5094_RS06755 (N5094_06755) 1546233..1546472 + 240 WP_014610939.1 CopG family ribbon-helix-helix protein -
N5094_RS06760 (N5094_06760) 1546462..1546746 + 285 WP_261762692.1 type II toxin-antitoxin system RelE/ParE family toxin -
N5094_RS06765 (N5094_06765) 1546818..1547234 - 417 WP_088585313.1 DUF86 domain-containing protein Toxin
N5094_RS06770 (N5094_06770) 1547227..1547649 - 423 WP_088585314.1 nucleotidyltransferase domain-containing protein Antitoxin
N5094_RS06775 (N5094_06775) 1548152..1548412 + 261 WP_086904670.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
N5094_RS06780 (N5094_06780) 1548414..1548761 + 348 WP_055647497.1 type II toxin-antitoxin system RelE/ParE family toxin -
N5094_RS06785 (N5094_06785) 1548973..1550181 + 1209 WP_261762693.1 molecular chaperone DnaJ -
N5094_RS06790 (N5094_06790) 1550975..1551391 - 417 WP_261762694.1 type II toxin-antitoxin system YafO family toxin -
N5094_RS06795 (N5094_06795) 1551382..1551699 - 318 WP_261762695.1 antitoxin of toxin-antitoxin stability system -
N5094_RS06800 (N5094_06800) 1551808..1551987 + 180 Protein_1311 IS66 family transposase -
N5094_RS06805 (N5094_06805) 1552360..1552566 - 207 Protein_1312 integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(12-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(9-96)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16056.55 Da        Isoelectric Point: 7.3244

>T259105 WP_088585313.1 NZ_CP104755:c1547234-1546818 [Shewanella putrefaciens]
MNDIIINKIATIKRCIKRIQQVYGDGSMFKQDFTLQDSVILNLQRCCEASIDIANHINRQQQLGIPQSSRDSFTLLSQNK
IINQQLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIEVIKFCPRMSY

Download         Length: 417 bp

Antitoxin


Download         Length: 141 a.a.        Molecular weight: 15861.89 Da        Isoelectric Point: 5.1231

>AT259105 WP_088585314.1 NZ_CP104755:c1547649-1547227 [Shewanella putrefaciens]
MQQLNESIIINLLQDNIPQLRLIYLFGSYAQGTQHRNSDIDIAVLADVTLDNIARWQLAQKLASALDTDVDLVDLRTAST
VLCQQVVTQGKRLWGTRQDDEIFAVKTISMYQHLQAERQAIIDDATAKTTANDHRGRHFE

Download         Length: 423 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References