Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Xre
Location 19827..20544 Replicon plasmid unnamed1
Accession NZ_CP104746
Organism Erwinia pyrifoliae strain CP20113301

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NYP80_RS19360 Protein ID WP_261648169.1
Coordinates 19827..20234 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NYP80_RS19365 Protein ID WP_261648134.1
Coordinates 20227..20544 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP80_RS19315 (NYP80_19315) 15425..15901 + 477 WP_261648160.1 hypothetical protein -
NYP80_RS19320 (NYP80_19320) 15990..16403 - 414 WP_261648161.1 relaxosome protein TraM -
NYP80_RS19325 (NYP80_19325) 16902..17036 - 135 WP_261648162.1 hypothetical protein -
NYP80_RS19330 (NYP80_19330) 17104..17298 - 195 WP_261648163.1 hypothetical protein -
NYP80_RS19335 (NYP80_19335) 17350..17679 - 330 WP_261648164.1 hypothetical protein -
NYP80_RS19340 (NYP80_19340) 17777..17995 - 219 WP_261648165.1 hypothetical protein -
NYP80_RS19345 (NYP80_19345) 17988..18254 - 267 WP_261648166.1 hypothetical protein -
NYP80_RS19350 (NYP80_19350) 18266..18808 - 543 WP_261648167.1 hypothetical protein -
NYP80_RS19355 (NYP80_19355) 18852..19367 - 516 WP_261648168.1 DnaJ domain-containing protein -
NYP80_RS19360 (NYP80_19360) 19827..20234 + 408 WP_261648169.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYP80_RS19365 (NYP80_19365) 20227..20544 + 318 WP_261648134.1 helix-turn-helix domain-containing protein Antitoxin
NYP80_RS19370 (NYP80_19370) 20949..21932 + 984 WP_261648135.1 recombinase family protein -
NYP80_RS19375 (NYP80_19375) 21955..22290 - 336 WP_044242374.1 hypothetical protein -
NYP80_RS19380 (NYP80_19380) 22287..22994 - 708 WP_261648136.1 ParA family protein -
NYP80_RS19385 (NYP80_19385) 24162..25025 - 864 WP_191928390.1 incFII family plasmid replication initiator RepA -
NYP80_RS19390 (NYP80_19390) 25018..25092 - 75 WP_261648170.1 RepA leader peptide Tap -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..40042 40042


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(7-131)

Antitoxin

Cro/C1-type helix-turn-helix domain

(49-90)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14973.22 Da        Isoelectric Point: 5.2929

>T259100 WP_261648169.1 NZ_CP104746:19827-20234 [Erwinia pyrifoliae]
MDALSVMGIYLTSEFETERQKARISNAMLRKAAKAIFSGLPGDPLGKFTFKKRLGLPGVGARDGARSIVFFNDGDNIFFF
DMYLKSGLSKKKGKELEDDEIDAYCNIAKDFISMSPATINKLLSDKELVEVNCDD

Download         Length: 408 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11620.56 Da        Isoelectric Point: 10.8279

>AT259100 WP_261648134.1 NZ_CP104746:20227-20544 [Erwinia pyrifoliae]
MTERLKRIQGMAERYNKLGVVKDETVAAIDAAVAARNIPAIRVMTGSQIKEVRTRYNMSQAALAITTGMSVESVSKWERN
ESKPNKAALRIINIIDTKGPQVFMA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References