Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 767242..767902 Replicon chromosome
Accession NZ_CP104745
Organism Erwinia pyrifoliae strain CP20113301

Toxin (Protein)


Gene name cptA Uniprot ID D2T6A5
Locus tag NYP80_RS03695 Protein ID WP_014539414.1
Coordinates 767489..767902 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NYP80_RS03690 Protein ID WP_012669171.1
Coordinates 767242..767508 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP80_RS03670 (NYP80_03670) 764247..764456 + 210 WP_259816865.1 SDR family oxidoreductase -
NYP80_RS03675 (NYP80_03675) 764550..765158 - 609 WP_012669174.1 HD domain-containing protein -
NYP80_RS03680 (NYP80_03680) 765370..766029 + 660 WP_012669173.1 hemolysin III family protein -
NYP80_RS03685 (NYP80_03685) 766030..767016 - 987 WP_259826094.1 tRNA-modifying protein YgfZ -
NYP80_RS03690 (NYP80_03690) 767242..767508 + 267 WP_012669171.1 FAD assembly factor SdhE Antitoxin
NYP80_RS03695 (NYP80_03695) 767489..767902 + 414 WP_014539414.1 protein YgfX Toxin
NYP80_RS03700 (NYP80_03700) 768026..768544 - 519 WP_012669169.1 flavodoxin FldB -
NYP80_RS03705 (NYP80_03705) 768590..769543 - 954 WP_259826095.1 DMT family transporter -
NYP80_RS03710 (NYP80_03710) 769859..770752 + 894 WP_014543356.1 site-specific tyrosine recombinase XerD -
NYP80_RS03715 (NYP80_03715) 770798..771502 + 705 WP_012669166.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-130)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16057.13 Da        Isoelectric Point: 12.3470

>T259094 WP_014539414.1 NZ_CP104745:767489-767902 [Erwinia pyrifoliae]
VVLWQCELRQSKLAQRLSLLLHGAVMLALLLPAWPASAGLVRMLLLVLVLLECIRSRRRIRRRQGDVALLGGHALRWRQR
EWRILSRPWLTRQAILLSLRDAKGERERLWLFADGMADSHWRRLRMQLLNNKEQGNG

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10482.07 Da        Isoelectric Point: 6.4605

>AT259094 WP_012669171.1 NZ_CP104745:767242-767508 [Erwinia pyrifoliae]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDGDKRLFVRLLESDDPDLFNWLMNHGEPADAELKRMVLLIQQRN
KQRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D2T6A5

Antitoxin

Source ID Structure

References