259093

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 522683..523199 Replicon chromosome
Accession NZ_CP104745
Organism Erwinia pyrifoliae strain CP20113301

Toxin (Protein)


Gene name relE Uniprot ID D2T7S6
Locus tag NYP80_RS02385 Protein ID WP_012669379.1
Coordinates 522683..522967 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D2T7S5
Locus tag NYP80_RS02390 Protein ID WP_012669378.1
Coordinates 522957..523199 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYP80_RS02355 (NYP80_02355) 520020..520424 + 405 WP_259817782.1 helix-turn-helix domain-containing protein -
NYP80_RS02360 (NYP80_02360) 520507..520809 + 303 WP_261647977.1 type I toxin-antitoxin system SymE family toxin -
NYP80_RS02365 (NYP80_02365) 520868..521161 - 294 WP_261647978.1 hypothetical protein -
NYP80_RS02370 (NYP80_02370) 521158..521568 - 411 WP_261647979.1 hypothetical protein -
NYP80_RS02375 (NYP80_02375) 521687..521869 - 183 WP_081441632.1 hypothetical protein -
NYP80_RS02380 (NYP80_02380) 522004..522180 + 177 WP_157861020.1 hypothetical protein -
NYP80_RS02385 (NYP80_02385) 522683..522967 - 285 WP_012669379.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYP80_RS02390 (NYP80_02390) 522957..523199 - 243 WP_012669378.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NYP80_RS02395 (NYP80_02395) 523460..524515 - 1056 WP_261647980.1 site-specific tyrosine recombinase XerC -
NYP80_RS02400 (NYP80_02400) 524730..527426 - 2697 WP_261647981.1 CHC2 zinc finger domain-containing protein -
NYP80_RS02405 (NYP80_02405) 527539..527940 + 402 WP_012669375.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 507712..573448 65736


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11123.03 Da        Isoelectric Point: 10.3769

>T259093 WP_012669379.1 NZ_CP104745:c522967-522683 [Erwinia pyrifoliae]
MSYELVFDPRALKEWKKLGATVREQFKKKLAEVLVNPRVESARLREYPDCYKIKLKSSGYRLVYQVQDEQLVVFVVATGK
RERLQVYRDAGKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9070.45 Da        Isoelectric Point: 4.6310

>AT259093 WP_012669378.1 NZ_CP104745:c523199-522957 [Erwinia pyrifoliae]
MATLNVRLDDKLKSKAYAVLDELDVSPTEAVRLLFQYIAENERLPLKTLTVSDEEDALLKTVRERLASPQKGIRVTLDEL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB D2T7S6

Antitoxin

Source ID Structure
AlphaFold DB D2T7S5

References