Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4666894..4667429 Replicon chromosome
Accession NZ_CP104733
Organism Pectobacterium sp. F1-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NAL19_RS20985 Protein ID WP_263058353.1
Coordinates 4667142..4667429 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag NAL19_RS20980 Protein ID WP_010281712.1
Coordinates 4666894..4667145 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL19_RS20955 (NAL19_4490) 4662542..4663053 - 512 Protein_4086 phenolic acid decarboxylase -
NAL19_RS20960 (NAL19_4492) 4663153..4664025 + 873 WP_263058349.1 LysR family transcriptional regulator -
NAL19_RS20965 (NAL19_4493) 4664052..4664672 - 621 WP_263058350.1 LysE family translocator -
NAL19_RS20970 (NAL19_4494) 4664941..4665696 + 756 WP_263058351.1 thiol:disulfide interchange protein DsbG -
NAL19_RS20975 (NAL19_4495) 4665731..4666636 - 906 WP_263058352.1 siderophore-interacting protein -
NAL19_RS20980 (NAL19_4497) 4666894..4667145 + 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NAL19_RS20985 (NAL19_4498) 4667142..4667429 + 288 WP_263058353.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NAL19_RS20990 4667530..4668884 - 1355 Protein_4093 glutathione-disulfide reductase -
NAL19_RS20995 (NAL19_4502) 4669013..4669855 - 843 WP_180742117.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
NAL19_RS21000 (NAL19_4503) 4670074..4670802 + 729 WP_263058354.1 DUF1266 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11025.10 Da        Isoelectric Point: 10.2271

>T259092 WP_263058353.1 NZ_CP104733:4667142-4667429 [Pectobacterium sp. F1-1]
MSYSVKFREDALKEWCKLDKTIQQQFAKKLKKCCENPHIPAAKLRGMKDCYKIKLRASGFRLVYEVIDDILVIAVVAVGK
RERSGVYNLASERMR

Download         Length: 288 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT259092 WP_010281712.1 NZ_CP104733:4666894-4667145 [Pectobacterium sp. F1-1]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References