Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3114751..3115476 Replicon chromosome
Accession NZ_CP104733
Organism Pectobacterium sp. F1-1

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag NAL19_RS13845 Protein ID WP_137742059.1
Coordinates 3114751..3115071 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID A0A1V2R6J7
Locus tag NAL19_RS13850 Protein ID WP_039360467.1
Coordinates 3115141..3115476 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL19_RS13815 (NAL19_2990) 3109984..3110187 - 204 WP_225085100.1 protein DsrB -
NAL19_RS13820 (NAL19_2991) 3110398..3111813 + 1416 WP_263057643.1 diguanylate cyclase -
NAL19_RS13825 (NAL19_2992) 3112091..3112309 + 219 WP_263057644.1 KTSC domain-containing protein -
NAL19_RS13830 (NAL19_2993) 3112708..3112866 + 159 WP_263057645.1 hypothetical protein -
NAL19_RS13835 (NAL19_2994) 3113469..3113666 - 198 WP_263057646.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
NAL19_RS13840 (NAL19_2995) 3113800..3114633 - 834 WP_137742060.1 DUF4942 domain-containing protein -
NAL19_RS13845 (NAL19_2996) 3114751..3115071 - 321 WP_137742059.1 TA system toxin CbtA family protein Toxin
NAL19_RS13850 (NAL19_2997) 3115141..3115476 - 336 WP_039360467.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NAL19_RS13855 (NAL19_2998) 3115516..3115989 - 474 WP_039360464.1 DNA repair protein RadC -
NAL19_RS13860 (NAL19_3001) 3116761..3117072 - 312 WP_263057647.1 hypothetical protein -
NAL19_RS13865 (NAL19_3002) 3117085..3117372 - 288 WP_263057648.1 hypothetical protein -
NAL19_RS13870 (NAL19_3003) 3117396..3117899 - 504 WP_263057649.1 hypothetical protein -
NAL19_RS13875 (NAL19_3004) 3117896..3118624 - 729 WP_180742545.1 WYL domain-containing protein -
NAL19_RS13880 (NAL19_3005) 3119056..3119940 - 885 WP_263057650.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - motA / flhC / flhD 3103138..3135857 32719


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-105)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12027.80 Da        Isoelectric Point: 5.6700

>T259089 WP_137742059.1 NZ_CP104733:c3115071-3114751 [Pectobacterium sp. F1-1]
MQTSSAIPPREDNPCASPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIDAGITLLNAINFLVEKYELVRIDRNGF
SWQKQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12444.16 Da        Isoelectric Point: 6.6303

>AT259089 WP_039360467.1 NZ_CP104733:c3115476-3115141 [Pectobacterium sp. F1-1]
MSLSDSPEWGLKRAVTPQFGARLVQEGHSLHYLADRASVIGAFSKTEARHLEQIFPELIKQLEQKLRTGELNPHKQGCIT
LHCNEWTCEADTLGSFGYVYIVIYPISAATQ

Download         Length: 336 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R6J7

References