Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1570108..1570661 Replicon chromosome
Accession NZ_CP104733
Organism Pectobacterium sp. F1-1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag NAL19_RS06860 Protein ID WP_263059204.1
Coordinates 1570347..1570661 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID A0A3S1FM98
Locus tag NAL19_RS06855 Protein ID WP_029729596.1
Coordinates 1570108..1570344 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL19_RS06845 (NAL19_1472) 1565812..1568121 - 2310 WP_263059202.1 TerB N-terminal domain-containing protein -
NAL19_RS06850 (NAL19_1473) 1568846..1569790 + 945 WP_263059203.1 zincin-like metallopeptidase domain-containing protein -
NAL19_RS06855 (NAL19_1474) 1570108..1570344 + 237 WP_029729596.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
NAL19_RS06860 (NAL19_1475) 1570347..1570661 + 315 WP_263059204.1 CcdB family protein Toxin
NAL19_RS06865 (NAL19_1477) 1571172..1572341 + 1170 WP_263059205.1 hypothetical protein -
NAL19_RS06870 (NAL19_1478) 1572577..1573719 + 1143 WP_263059206.1 reverse transcriptase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1547475..1602754 55279


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11607.58 Da        Isoelectric Point: 7.9859

>T259088 WP_263059204.1 NZ_CP104733:1570347-1570661 [Pectobacterium sp. F1-1]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVIRLTDGKEYAVMTHELASIPVQALG
TVFCDVSQYRTQVKAAIDFLIDGF

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8927.96 Da        Isoelectric Point: 6.4612

>AT259088 WP_029729596.1 NZ_CP104733:1570108-1570344 [Pectobacterium sp. F1-1]
MTAKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRSHEAKKWQEENREALAALNRFHDEQGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A3S1FM98

References