Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1226106..1226731 Replicon chromosome
Accession NZ_CP104733
Organism Pectobacterium sp. F1-1

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag NAL19_RS05295 Protein ID WP_005976087.1
Coordinates 1226106..1226309 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag NAL19_RS05300 Protein ID WP_263058990.1
Coordinates 1226363..1226731 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL19_RS05265 (NAL19_1145) 1221621..1221959 + 339 WP_002208627.1 P-II family nitrogen regulator -
NAL19_RS05270 (NAL19_1146) 1221999..1223285 + 1287 WP_225087233.1 ammonium transporter AmtB -
NAL19_RS05275 (NAL19_1147) 1223363..1224226 - 864 WP_263058986.1 acyl-CoA thioesterase II -
NAL19_RS05280 (NAL19_1148) 1224439..1225020 + 582 WP_225087235.1 YbaY family lipoprotein -
NAL19_RS05285 (NAL19_1149) 1225041..1225361 - 321 WP_015839360.1 MGMT family protein -
NAL19_RS05295 (NAL19_1150) 1226106..1226309 - 204 WP_005976087.1 HHA domain-containing protein Toxin
NAL19_RS05300 (NAL19_1151) 1226363..1226731 - 369 WP_263058990.1 Hha toxicity modulator TomB Antitoxin
NAL19_RS05305 (NAL19_1152) 1227328..1227474 - 147 WP_263058991.1 type B 50S ribosomal protein L36 -
NAL19_RS05310 (NAL19_1153) 1227492..1227740 - 249 WP_225087236.1 type B 50S ribosomal protein L31 -
NAL19_RS05315 (NAL19_1154) 1227971..1231099 - 3129 WP_263058992.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T259086 WP_005976087.1 NZ_CP104733:c1226309-1226106 [Pectobacterium sp. F1-1]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT259086 WP_263058990.1 NZ_CP104733:c1226731-1226363 [Pectobacterium sp. F1-1]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINIQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure

References