Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 794802..795462 Replicon chromosome
Accession NZ_CP104733
Organism Pectobacterium sp. F1-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NAL19_RS03520 Protein ID WP_250160548.1
Coordinates 795088..795462 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID C6D8Y5
Locus tag NAL19_RS03515 Protein ID WP_012773340.1
Coordinates 794802..795068 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL19_RS03495 (NAL19_748) 790750..791754 - 1005 WP_263058766.1 LacI family DNA-binding transcriptional regulator -
NAL19_RS03500 (NAL19_749) 791809..792417 - 609 WP_263058767.1 HD domain-containing protein -
NAL19_RS03505 (NAL19_750) 792863..793510 + 648 WP_225086922.1 hemolysin III family protein -
NAL19_RS03510 (NAL19_751) 793565..794566 - 1002 WP_263058768.1 tRNA-modifying protein YgfZ -
NAL19_RS03515 (NAL19_752) 794802..795068 + 267 WP_012773340.1 FAD assembly factor SdhE Antitoxin
NAL19_RS03520 (NAL19_753) 795088..795462 + 375 WP_250160548.1 protein YgfX Toxin
NAL19_RS03525 (NAL19_754) 795530..796465 + 936 WP_263058769.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
NAL19_RS03530 (NAL19_755) 796531..796740 - 210 WP_263058770.1 hypothetical protein -
NAL19_RS03535 (NAL19_756) 796806..797326 - 521 Protein_683 flavodoxin FldB -
NAL19_RS03540 (NAL19_757) 797488..798813 - 1326 WP_263058771.1 MFS transporter -
NAL19_RS03545 (NAL19_758) 799143..800042 + 900 WP_225086929.1 site-specific tyrosine recombinase XerD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-119)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 14659.31 Da        Isoelectric Point: 10.6585

>T259085 WP_250160548.1 NZ_CP104733:795088-795462 [Pectobacterium sp. F1-1]
MQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQEWQIVKRPWLLKN
GVLLSLQAVNGKDRQQLWLASDSMGDDEWRHLRQLLLQQKNWAR

Download         Length: 375 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10465.94 Da        Isoelectric Point: 6.2223

>AT259085 WP_012773340.1 NZ_CP104733:794802-795068 [Pectobacterium sp. F1-1]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLSDSDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7W2E501

References