259078

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 7352365..7352870 Replicon chromosome
Accession NZ_CP104727
Organism Pseudomonas citronellolis strain G5.80

Toxin (Protein)


Gene name parE Uniprot ID W5IQ81
Locus tag N5P21_RS32530 Protein ID WP_009614629.1
Coordinates 7352589..7352870 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID W5IQE2
Locus tag N5P21_RS32525 Protein ID WP_009614631.1
Coordinates 7352365..7352592 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P21_RS32505 (N5P21_32525) 7348986..7349387 - 402 WP_261747239.1 GFA family protein -
N5P21_RS32510 (N5P21_32530) 7349399..7350130 - 732 WP_261747240.1 phytanoyl-CoA dioxygenase family protein -
N5P21_RS32515 (N5P21_32535) 7350127..7351053 - 927 WP_261747241.1 LysR family transcriptional regulator -
N5P21_RS32520 (N5P21_32540) 7351128..7352084 - 957 WP_261747242.1 agmatinase -
N5P21_RS32525 (N5P21_32545) 7352365..7352592 + 228 WP_009614631.1 CopG family ribbon-helix-helix protein Antitoxin
N5P21_RS32530 (N5P21_32550) 7352589..7352870 + 282 WP_009614629.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5P21_RS32535 (N5P21_32555) 7353130..7353861 + 732 WP_261747243.1 RcnB family protein -
N5P21_RS32540 (N5P21_32560) 7353902..7354183 - 282 WP_069862794.1 DUF2218 domain-containing protein -
N5P21_RS32545 (N5P21_32565) 7354281..7355198 + 918 WP_261747244.1 LysR family transcriptional regulator -
N5P21_RS32550 (N5P21_32570) 7355257..7355712 + 456 WP_116425958.1 GNAT family N-acetyltransferase -
N5P21_RS32555 (N5P21_32575) 7355709..7356326 - 618 WP_261747245.1 DUF1826 domain-containing protein -
N5P21_RS32560 (N5P21_32580) 7356326..7357528 - 1203 WP_074980504.1 zinc metallochaperone GTPase ZigA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-88)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10251.74 Da        Isoelectric Point: 6.4614

>T259078 WP_009614629.1 NZ_CP104727:7352589-7352870 [Pseudomonas citronellolis]
MSLQWTHKAAADLDGLYDHYVVLIGPEKALKAIQDVVGQVKALADLSLSSVGRPSEVPGVRELPLERWPYQAAYRVKGRD
VQILRIDSVDNPG

Download         Length: 282 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8357.42 Da        Isoelectric Point: 6.6405

>AT259078 WP_009614631.1 NZ_CP104727:7352365-7352592 [Pseudomonas citronellolis]
MTTVISFRADDALAKALDQLARATHRDRPYHLRQALAQYLERQSWHVAAIDEGLADANAGHLLPHAEIEAKWGLA

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A5D1B8

Antitoxin

Source ID Structure
AlphaFold DB A0A1S1GJG7

References