259076

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 6661844..6663506 Replicon chromosome
Accession NZ_CP104727
Organism Pseudomonas citronellolis strain G5.80

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag N5P21_RS29340 Protein ID WP_261747017.1
Coordinates 6661844..6662680 (+) Length 279 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID A0A127MMF0
Locus tag N5P21_RS29345 Protein ID WP_043315318.1
Coordinates 6662685..6663506 (+) Length 274 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P21_RS29310 (N5P21_29330) 6657259..6657411 + 153 WP_261747015.1 hypothetical protein -
N5P21_RS29315 (N5P21_29335) 6657856..6658698 + 843 WP_261748805.1 ABC transporter ATP-binding protein -
N5P21_RS29320 (N5P21_29340) 6658785..6659717 + 933 Protein_5790 ABC transporter substrate-binding protein -
N5P21_RS29325 (N5P21_29345) 6659734..6660507 + 774 WP_261747016.1 ABC transporter permease -
N5P21_RS29330 (N5P21_29350) 6660518..6661279 + 762 WP_256514150.1 SDR family oxidoreductase -
N5P21_RS29335 (N5P21_29355) 6661291..6661824 + 534 WP_253389938.1 cupin domain-containing protein -
N5P21_RS29340 (N5P21_29360) 6661844..6662680 + 837 WP_261747017.1 alpha/beta fold hydrolase Toxin
N5P21_RS29345 (N5P21_29365) 6662685..6663506 + 822 WP_043315318.1 IclR family transcriptional regulator Antitoxin
N5P21_RS29350 (N5P21_29370) 6663503..6664300 + 798 WP_261747018.1 SDR family oxidoreductase -
N5P21_RS29355 (N5P21_29375) 6664293..6665975 + 1683 WP_116426058.1 thiamine pyrophosphate-binding protein -
N5P21_RS29360 (N5P21_29380) 6665986..6666789 + 804 WP_043315322.1 aspartate dehydrogenase -
N5P21_RS29365 (N5P21_29385) 6666800..6668287 + 1488 WP_261747019.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(40-268)

Antitoxin

Transcription regulator IclR, C-terminal

(133-254)


Sequences

Toxin        


Download         Length: 279 a.a.        Molecular weight: 29300.81 Da        Isoelectric Point: 7.0138

>T259076 WP_261747017.1 NZ_CP104727:6661844-6662680 [Pseudomonas citronellolis]
MSTAAAWQADLERDFPQRLVRRGEVVSAWREAGAADAPALVLLHGIGSGAASWLPLAQCLKARARLIAWDAPGYGESTPL
AEAAPRAEAYMQRLRELLDALDVQRCVLLGHSLGALTALALANAEPRLIAHLLLLSPARGYGARPDEGEAVRSRRLAALA
SEGIAGLAERRAPAMLGASPSAEALAWVRGNMARLKPHGYRQAVELLCGDDLLRLGRPPIPVEVLCGSEDGITPPAACRE
VAAALAAPFRLVPGAGHASPIECPEALAGHLVRFLDKD

Download         Length: 837 bp

Antitoxin


Download         Length: 274 a.a.        Molecular weight: 30342.91 Da        Isoelectric Point: 6.7546

>AT259076 WP_043315318.1 NZ_CP104727:6662685-6663506 [Pseudomonas citronellolis]
MSTDTLTENQERYMVPGLERGLTLLGEFTRHDRTLTAPELARRLQLPRTTIFRLLATLEALGFVTRSGNEYRLGMAVLRL
GFEYLASLELTELGQPILRRLCDAIGYSCNLVVRDGRNIVYVAKISPPSILTSAVNVGTRLPAHATVLGRILLEDLDLAA
LRELYPEKQLERFSEGTPRNTEELFDLVQNDRLRGYALSEGFFEASISTVAAPVRDHTGRVCAAMGVTIPATRIAEHLLE
PLVRQVRNSAEELSGLLGHMPNPNVLSLQRVHS

Download         Length: 822 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A127MMF0

References