259072

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE(toxin)
Location 4291705..4292293 Replicon chromosome
Accession NZ_CP104727
Organism Pseudomonas citronellolis strain G5.80

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N5P21_RS18705 Protein ID WP_116425311.1
Coordinates 4291943..4292293 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A4Z0IXF0
Locus tag N5P21_RS18700 Protein ID WP_074979635.1
Coordinates 4291705..4291962 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5P21_RS18665 (N5P21_18685) 4287491..4287868 - 378 WP_116425309.1 S24 family peptidase -
N5P21_RS18670 (N5P21_18690) 4288012..4288230 + 219 WP_009619937.1 hypothetical protein -
N5P21_RS18675 (N5P21_18695) 4288357..4288572 - 216 WP_009619935.1 hypothetical protein -
N5P21_RS18685 (N5P21_18705) 4289265..4289684 + 420 WP_116425310.1 LytTR family DNA-binding domain-containing protein -
N5P21_RS18690 (N5P21_18710) 4289990..4290415 - 426 WP_074979636.1 hydrogenase -
N5P21_RS18695 (N5P21_18715) 4290847..4291197 + 351 WP_009619928.1 hypothetical protein -
N5P21_RS18700 (N5P21_18720) 4291705..4291962 + 258 WP_074979635.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N5P21_RS18705 (N5P21_18725) 4291943..4292293 + 351 WP_116425311.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N5P21_RS18715 (N5P21_18735) 4292908..4293333 - 426 WP_253390771.1 lipocalin-like domain-containing protein -
N5P21_RS18720 (N5P21_18740) 4293338..4294174 - 837 WP_253390770.1 alpha/beta fold hydrolase -
N5P21_RS18725 (N5P21_18745) 4294171..4295130 - 960 WP_253390769.1 VOC family protein -
N5P21_RS18730 (N5P21_18750) 4295168..4295914 - 747 WP_253390768.1 glucose 1-dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(26-106)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13499.53 Da        Isoelectric Point: 10.5002

>T259072 WP_116425311.1 NZ_CP104727:4291943-4292293 [Pseudomonas citronellolis]
MTSKTGNNKQIKAPQQDQEDIKQYTLKFKETALKEWDRLKGPVKTQLIKKLGERLVNPRVEKDKLHGSENKDRYKIKLSA
SGYRLVYQVHDTEIVVEVVAVGKRERSAVYNESKKR

Download         Length: 351 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9373.65 Da        Isoelectric Point: 4.3516

>AT259072 WP_074979635.1 NZ_CP104727:4291705-4291962 [Pseudomonas citronellolis]
MPHALLADVTASITELKKDPMGTVGAGMGHAVAILNRNEPVFYAVPADEYERMIELLDDIYLGRLADERKDESSVTVSLD
DLKNR

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A4Z0IXF0

References