Detailed information of TA system TA259071

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 2051611..2053050
• Replicon: chromosome
• Accession: NZ_CP104727
• Organism: Pseudomonas citronellolis strain G5.80

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: N5P21_RS09125
• Protein ID: WP_116423104.1
• Coordinates: 2051611..2052180 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: N5P21_RS09130
• Protein ID: WP_261747948.1
• Coordinates: 2052190..2053050 (+)
• Length: 287 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N5P21_RS09120 (N5P21_09130)	2047883..2051359	-	3477	WP_249917426.1	hybrid sensor histidine kinase/response regulator	-
N5P21_RS09125 (N5P21_09135)	2051611..2052180	+	570	WP_116423104.1	GNAT family protein	Toxin
N5P21_RS09130 (N5P21_09140)	2052190..2053050	+	861	WP_261747948.1	AraC family transcriptional regulator	Antitoxin
N5P21_RS09135 (N5P21_09145)	2053461..2055335	+	1875	WP_253409745.1	MFS transporter	-
N5P21_RS09140 (N5P21_09150)	2055385..2055594	-	210	WP_009620558.1	cold-shock protein	-
N5P21_RS09145 (N5P21_09155)	2055786..2056100	-	315	WP_009620556.1	quaternary ammonium compound efflux SMR transporter SugE	-
N5P21_RS09150 (N5P21_09160)	2056243..2057187	-	945	WP_253392329.1	bile acid:sodium symporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• AraC-type arabinose-binding/dimerisation domain (20-148)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21092.38 Da
• Isoelectric Point: 10.2630

>T259071 WP_116423104.1 NZ_CP104727:2051611-2052180 [Pseudomonas citronellolis]
MFRPSPITLQRGALRLEPMVEADVPDLVALAEANREALRFMSAPQRPDWYRNSLAEQREGRALPLVVRLGNQLVGTTRFM
DFLPALPACEIGGTWLDAAQHGTGLNASIKYLMLRQAFDNWKMVRVQLKTAASNLRSQRAIEKLGAVREGVLRNHRRLAG
GRLDDSVLYSITDLEWPQVKAALEAGFIG

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 287 a.a.
• Molecular weight: 31638.96 Da
• Isoelectric Point: 8.3438

>AT259071 WP_261747948.1 NZ_CP104727:2052190-2053050 [Pseudomonas citronellolis]
MPLDSAHGEQTRFWRAQELGGLELLHARFIEQRFAPHVHEGFALVLIEQGAQRFRHRGAEHLAPSGSLVLINPDEVHTGS
KAHETGWLYRGFYPEIGQVGSVLDELELGGRGLPTFDASVLHDPELSRAFLHVHRLLESNASSLERQTCWREALLLLFQR
HARVPEARPAGQEPQAVARARELLAARLVEPPSLEELAAAVNLSPFHFARVFRKATGLPPHAWIKQRRLEQARALLKGGC
APASVAAQLGYADQSHLSRQFKQAYGVAPGEYRQACGRSGLPPGNL

Nucleotide

• Length: 861 bp